2fse: Difference between revisions
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[[Image:2fse.gif|left|200px]] | [[Image:2fse.gif|left|200px]] | ||
'''Crystallographic structure of a rheumatoid arthritis MHC susceptibility allele, HLA-DR1 (DRB1*0101), complexed with the immunodominant determinant of human type II collagen''' | {{Structure | ||
|PDB= 2fse |SIZE=350|CAPTION= <scene name='initialview01'>2fse</scene>, resolution 3.100Å | |||
|SITE= | |||
|LIGAND= | |||
|ACTIVITY= | |||
|GENE= COL2A1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | |||
}} | |||
'''Crystallographic structure of a rheumatoid arthritis MHC susceptibility allele, HLA-DR1 (DRB1*0101), complexed with the immunodominant determinant of human type II collagen''' | |||
==Overview== | ==Overview== | ||
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==Disease== | ==Disease== | ||
Known diseases associated with this structure: Achondrogenesis-hypochondrogenesis, type II OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=120140 120140]], Epiphyseal dysplasia, multiple, with myopia and deafness OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=120140 120140]], Kniest dysplasia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=120140 120140]], Osteoarthrosis OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=120140 120140]], | Known diseases associated with this structure: Achondrogenesis-hypochondrogenesis, type II OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=120140 120140]], Epiphyseal dysplasia, multiple, with myopia and deafness OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=120140 120140]], Kniest dysplasia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=120140 120140]], Osteoarthrosis OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=120140 120140]], SED congenita OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=120140 120140]], SED, Namaqualand type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=120140 120140]], SMED Strudwick type OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=120140 120140]], Spondyloperipheral dysplasia OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=120140 120140]], Stickler syndrome, type I OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=120140 120140]], Vitreoretinopathy with phalangeal epiphyseal dysplasia ( OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=120140 120140]] | ||
==About this Structure== | ==About this Structure== | ||
2FSE is a [ | 2FSE is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FSE OCA]. | ||
==Reference== | ==Reference== | ||
Crystallographic structure of a rheumatoid arthritis MHC susceptibility allele, HLA-DR1 (DRB1*0101), complexed with the immunodominant determinant of human type II collagen., Rosloniec EF, Ivey RA 3rd, Whittington KB, Kang AH, Park HW, J Immunol. 2006 Sep 15;177(6):3884-92. PMID:[http:// | Crystallographic structure of a rheumatoid arthritis MHC susceptibility allele, HLA-DR1 (DRB1*0101), complexed with the immunodominant determinant of human type II collagen., Rosloniec EF, Ivey RA 3rd, Whittington KB, Kang AH, Park HW, J Immunol. 2006 Sep 15;177(6):3884-92. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16951351 16951351] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Mus musculus]] | [[Category: Mus musculus]] | ||
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[[Category: rheumatoid arthritis]] | [[Category: rheumatoid arthritis]] | ||
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