Practical Guide to Homology Modeling: Difference between revisions
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===Hydrophobic Core=== | ====Hydrophobic Core==== | ||
Soluble proteins should have a well-defined hydrophobic core. To see this in ''FirstGlance'', under the ''Views'' tab, click ''Hydrophobic/Polar'', and then turn on the ''Slab'' button. If the protein has multiple domains, each domain should have a hydrophobic core. If there is no hydrophobic core in a soluble protein model, the model most likely has very substantial errors. | Soluble proteins should have a well-defined hydrophobic core. To see this in ''FirstGlance'', under the ''Views'' tab, click ''Hydrophobic/Polar'', and then turn on the ''Slab'' button. If the protein has multiple domains, each domain should have a hydrophobic core. If there is no hydrophobic core in a soluble protein model, the model most likely has very substantial errors. | ||
