2fsz: Difference between revisions

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[[Image:2fsz.gif|left|200px]]<br /><applet load="2fsz" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2fsz.gif|left|200px]]
caption="2fsz, resolution 2.200&Aring;" />
 
'''A second binding site for hydroxytamoxifen within the coactivator-binding groove of estrogen receptor beta'''<br />
{{Structure
|PDB= 2fsz |SIZE=350|CAPTION= <scene name='initialview01'>2fsz</scene>, resolution 2.200&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=OHT:4-HYDROXYTAMOXIFEN'>OHT</scene>
|ACTIVITY=
|GENE= ESR2, ESTRB, NR3A2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''A second binding site for hydroxytamoxifen within the coactivator-binding groove of estrogen receptor beta'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2FSZ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=OHT:'>OHT</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FSZ OCA].  
2FSZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FSZ OCA].  


==Reference==
==Reference==
A second binding site for hydroxytamoxifen within the coactivator-binding groove of estrogen receptor beta., Wang Y, Chirgadze NY, Briggs SL, Khan S, Jensen EV, Burris TP, Proc Natl Acad Sci U S A. 2006 Jun 27;103(26):9908-11. Epub 2006 Jun 16. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16782818 16782818]
A second binding site for hydroxytamoxifen within the coactivator-binding groove of estrogen receptor beta., Wang Y, Chirgadze NY, Briggs SL, Khan S, Jensen EV, Burris TP, Proc Natl Acad Sci U S A. 2006 Jun 27;103(26):9908-11. Epub 2006 Jun 16. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16782818 16782818]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: nuclear hormone binding domain]]
[[Category: nuclear hormone binding domain]]


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