2ftd: Difference between revisions

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[[Image:2ftd.jpg|left|200px]]<br /><applet load="2ftd" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2ftd.jpg|left|200px]]
caption="2ftd, resolution 2.55&Aring;" />
 
'''Crystal structure of Cathepsin K complexed with 7-Methyl-Substituted Azepan-3-one compound'''<br />
{{Structure
|PDB= 2ftd |SIZE=350|CAPTION= <scene name='initialview01'>2ftd</scene>, resolution 2.55&Aring;
|SITE= <scene name='pdbsite=AC1:Ili+Binding+Site+For+Residue+A+300'>AC1</scene> and <scene name='pdbsite=AC2:Ili+Binding+Site+For+Residue+B+301'>AC2</scene>
|LIGAND= <scene name='pdbligand=ILI:N-[(1S)-1-({[(3S,4S,7R)-3-HYDROXY-7-METHYL-1-(PYRIDIN-2-YLSULFONYL)-2,3,4,7-TETRAHYDRO-1H-AZEPIN-4-YL]AMINO}CARBONYL)-3-METHYLBUTYL]-1-BENZOFURAN-2-CARBOXAMIDE'>ILI</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Cathepsin_K Cathepsin K], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.38 3.4.22.38]
|GENE= CTSK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9544 Macaca mulatta])
}}
 
'''Crystal structure of Cathepsin K complexed with 7-Methyl-Substituted Azepan-3-one compound'''
 


==About this Structure==
==About this Structure==
2FTD is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Macaca_mulatta Macaca mulatta] with <scene name='pdbligand=ILI:'>ILI</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Cathepsin_K Cathepsin K], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.22.38 3.4.22.38] Known structural/functional Sites: <scene name='pdbsite=AC1:Ili+Binding+Site+For+Residue+A+300'>AC1</scene> and <scene name='pdbsite=AC2:Ili+Binding+Site+For+Residue+B+301'>AC2</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FTD OCA].  
2FTD is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Macaca_mulatta Macaca mulatta]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FTD OCA].  
[[Category: Cathepsin K]]
[[Category: Cathepsin K]]
[[Category: Macaca mulatta]]
[[Category: Macaca mulatta]]
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[[Category: sulfhydryl proteinase]]
[[Category: sulfhydryl proteinase]]


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