2ftw: Difference between revisions

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[[Image:2ftw.gif|left|200px]]<br /><applet load="2ftw" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2ftw.gif|left|200px]]
caption="2ftw, resolution 2.050&Aring;" />
 
'''Crystal structure of dihydropyrimidinase from dictyostelium discoideum'''<br />
{{Structure
|PDB= 2ftw |SIZE=350|CAPTION= <scene name='initialview01'>2ftw</scene>, resolution 2.050&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene> and <scene name='pdbligand=MLI:MALONATE ION'>MLI</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Dihydropyrimidinase Dihydropyrimidinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.2 3.5.2.2]
|GENE= pyd2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=44689 Dictyostelium discoideum])
}}
 
'''Crystal structure of dihydropyrimidinase from dictyostelium discoideum'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2FTW is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Dictyostelium_discoideum Dictyostelium discoideum] with <scene name='pdbligand=ZN:'>ZN</scene> and <scene name='pdbligand=MLI:'>MLI</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Dihydropyrimidinase Dihydropyrimidinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.2 3.5.2.2] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FTW OCA].  
2FTW is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Dictyostelium_discoideum Dictyostelium discoideum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FTW OCA].  


==Reference==
==Reference==
The crystal structures of dihydropyrimidinases reaffirm the close relationship between cyclic amidohydrolases and explain their substrate specificity., Lohkamp B, Andersen B, Piskur J, Dobritzsch D, J Biol Chem. 2006 May 12;281(19):13762-76. Epub 2006 Mar 3. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16517602 16517602]
The crystal structures of dihydropyrimidinases reaffirm the close relationship between cyclic amidohydrolases and explain their substrate specificity., Lohkamp B, Andersen B, Piskur J, Dobritzsch D, J Biol Chem. 2006 May 12;281(19):13762-76. Epub 2006 Mar 3. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16517602 16517602]
[[Category: Dictyostelium discoideum]]
[[Category: Dictyostelium discoideum]]
[[Category: Dihydropyrimidinase]]
[[Category: Dihydropyrimidinase]]
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[[Category: beta-sandwich]]
[[Category: beta-sandwich]]


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