4wil: Difference between revisions
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''' | ==Crystal structure of DCoH2 S51T== | ||
<StructureSection load='4wil' size='340' side='right' caption='[[4wil]], [[Resolution|resolution]] 1.36Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4wil]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4WIL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4WIL FirstGlance]. <br> | |||
</td></tr><tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/4a-hydroxytetrahydrobiopterin_dehydratase 4a-hydroxytetrahydrobiopterin dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.96 4.2.1.96] </span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4wil FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4wil OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4wil RCSB], [http://www.ebi.ac.uk/pdbsum/4wil PDBsum]</span></td></tr> | |||
</table> | |||
[[Category: | == Function == | ||
[[http://www.uniprot.org/uniprot/PHS2_MOUSE PHS2_MOUSE]] Involved in tetrahydrobiopterin biosynthesis. Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2 (By similarity). Regulates the dimerization of homeodomain protein HNF-1-alpha and enhances its transcriptional activity. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: 4a-hydroxytetrahydrobiopterin dehydratase]] | |||
[[Category: Rose, R B]] | |||
[[Category: Wang, D]] | [[Category: Wang, D]] | ||
[[Category: | [[Category: Bifunctional]] | ||
[[Category: Coactivator]] | |||
[[Category: Kinetic stability]] | |||
[[Category: Lyase]] | |||
[[Category: Tetrahydrobiopterin recycling]] | |||
