2fwy: Difference between revisions
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[[Image:2fwy.jpg|left|200px]] | [[Image:2fwy.jpg|left|200px]] | ||
'''Structure of human Hsp90-alpha bound to the potent water soluble inhibitor PU-H64''' | {{Structure | ||
|PDB= 2fwy |SIZE=350|CAPTION= <scene name='initialview01'>2fwy</scene>, resolution 2.10Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=H64:8-(6-BROMO-BENZO[1,3]DIOXOL-5-YLSULFANYL)-9-(3-ISOPROPYLAMINO-PROPYL)-ADENINE'>H64</scene> | |||
|ACTIVITY= | |||
|GENE= HSPCA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | |||
}} | |||
'''Structure of human Hsp90-alpha bound to the potent water soluble inhibitor PU-H64''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
2FWY is a [ | 2FWY is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FWY OCA]. | ||
==Reference== | ==Reference== | ||
Structural and quantum chemical studies of 8-aryl-sulfanyl adenine class Hsp90 inhibitors., Immormino RM, Kang Y, Chiosis G, Gewirth DT, J Med Chem. 2006 Aug 10;49(16):4953-60. PMID:[http:// | Structural and quantum chemical studies of 8-aryl-sulfanyl adenine class Hsp90 inhibitors., Immormino RM, Kang Y, Chiosis G, Gewirth DT, J Med Chem. 2006 Aug 10;49(16):4953-60. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16884307 16884307] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: purine]] | [[Category: purine]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 16:57:45 2008'' | ||
