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== Introduction ==
== Introduction ==
All living organisms depend on P-type ATPase to pump cation across the membrane. They play a fundamental role in their metabolism and physiology. Ca2+ ATPase, a P-type ATPase, transports calcium ions across the membrane against a concentration gradient. These pumps clear cytoplasm of the second messenger, the calcium. It's very important to keep a low concentration of calcium in the cell for a good cell signaling.
All living organisms depend on P-type ATPase to pump cation across the membrane. They play a fundamental role in their metabolism and physiology. Ca2+ ATPase, a P-type ATPase, transports calcium ions across the membrane against a concentration gradient. These pumps clear cytoplasm of the second messenger, the calcium. It's very important to keep a low concentration of calcium in the cell for a good cell signaling.
We can found the PMCA (Plasma Membrane Ca2+ ATPase) which remove the calcium from the cell and the SERCA (Sarcoplasmic Endoplasmic Reticulum Ca2+ ATPase) which pumps calcium into the endoplasmique reticulum.
We can found the PMCA (Plasma Membrane Ca2+ ATPase) which remove the calcium from the cell and the SERCA (Sarcoplasmic Endoplasmic Reticulum Ca2+ ATPase) which pumps calcium into the endoplasmic reticulum.
The hydrolysis of one adenosine triphosphate (ATP) is essential for the functioning of the pump and the transport of one calcium ion.
The hydrolysis of one adenosine triphosphate (ATP) is essential for the functioning of the pump and the transport of one calcium ion.