2fyv: Difference between revisions

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[[Image:2fyv.jpg|left|200px]]<br /><applet load="2fyv" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2fyv.jpg|left|200px]]
caption="2fyv, resolution 1.900&Aring;" />
 
'''Golgi alpha-mannosidase II complex with an amino-salacinol carboxylate analog'''<br />
{{Structure
|PDB= 2fyv |SIZE=350|CAPTION= <scene name='initialview01'>2fyv</scene>, resolution 1.900&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>, <scene name='pdbligand=W72:6-DEOXY-6-[(2R,3R,4R)-3,4-DIHYDROXY-2-(HYDROXYMETHYL)PYRROLIDIN-1-YL]-L-GULONIC+ACID'>W72</scene> and <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Mannosyl-oligosaccharide_1,3-1,6-alpha-mannosidase Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.114 3.2.1.114]
|GENE=
}}
 
'''Golgi alpha-mannosidase II complex with an amino-salacinol carboxylate analog'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2FYV is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster] with <scene name='pdbligand=NAG:'>NAG</scene>, <scene name='pdbligand=PO4:'>PO4</scene>, <scene name='pdbligand=ZN:'>ZN</scene>, <scene name='pdbligand=W72:'>W72</scene> and <scene name='pdbligand=MPD:'>MPD</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Mannosyl-oligosaccharide_1,3-1,6-alpha-mannosidase Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.114 3.2.1.114] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FYV OCA].  
2FYV is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FYV OCA].  


==Reference==
==Reference==
Synthesis, enzymatic activity, and X-ray crystallography of an unusual class of amino acids., Chen W, Kuntz DA, Hamlet T, Sim L, Rose DR, Mario Pinto B, Bioorg Med Chem. 2006 Dec 15;14(24):8332-40. Epub 2006 Sep 28. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17010621 17010621]
Synthesis, enzymatic activity, and X-ray crystallography of an unusual class of amino acids., Chen W, Kuntz DA, Hamlet T, Sim L, Rose DR, Mario Pinto B, Bioorg Med Chem. 2006 Dec 15;14(24):8332-40. Epub 2006 Sep 28. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17010621 17010621]
[[Category: Drosophila melanogaster]]
[[Category: Drosophila melanogaster]]
[[Category: Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase]]
[[Category: Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase]]
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[[Category: glycosyl hydrolase family 38]]
[[Category: glycosyl hydrolase family 38]]


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