2fzs: Difference between revisions

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[[Image:2fzs.gif|left|200px]]<br /><applet load="2fzs" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2fzs.gif|left|200px]]
caption="2fzs, resolution 1.90&Aring;" />
 
'''Crystal structure of E. coli ClpP with a Peptide Chloromethyl Ketone Covalently Bound at the Active Site'''<br />
{{Structure
|PDB= 2fzs |SIZE=350|CAPTION= <scene name='initialview01'>2fzs</scene>, resolution 1.90&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=CMQ:N~2~-[(BENZYLOXY)CARBONYL]-N-[(1S,2S)-2-HYDROXY-1-(4-HYDROXYBENZYL)PROPYL]-L-LEUCINAMIDE'>CMQ</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Endopeptidase_Clp Endopeptidase Clp], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.92 3.4.21.92]
|GENE= clpP, lopP ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
}}
 
'''Crystal structure of E. coli ClpP with a Peptide Chloromethyl Ketone Covalently Bound at the Active Site'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2FZS is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=CMQ:'>CMQ</scene>, <scene name='pdbligand=PGE:'>PGE</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Endopeptidase_Clp Endopeptidase Clp], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.92 3.4.21.92] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FZS OCA].  
2FZS is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2FZS OCA].  


==Reference==
==Reference==
Crystal structure at 1.9A of E. coli ClpP with a peptide covalently bound at the active site., Szyk A, Maurizi MR, J Struct Biol. 2006 Oct;156(1):165-74. Epub 2006 Apr 21. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16682229 16682229]
Crystal structure at 1.9A of E. coli ClpP with a peptide covalently bound at the active site., Szyk A, Maurizi MR, J Struct Biol. 2006 Oct;156(1):165-74. Epub 2006 Apr 21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16682229 16682229]
[[Category: Endopeptidase Clp]]
[[Category: Endopeptidase Clp]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: z-leu-tyr chloromethyl ketone inhibitor]]
[[Category: z-leu-tyr chloromethyl ketone inhibitor]]


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