2g44: Difference between revisions

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[[Image:2g44.gif|left|200px]]<br /><applet load="2g44" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2g44.gif|left|200px]]
caption="2g44, resolution 2.65&Aring;" />
 
'''Human Estrogen Receptor Alpha Ligand-Binding Domain In Complex With OBCP-1M-G and A Glucocorticoid Receptor Interacting Protein 1 NR Box II Peptide'''<br />
{{Structure
|PDB= 2g44 |SIZE=350|CAPTION= <scene name='initialview01'>2g44</scene>, resolution 2.65&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=T3O:4-[(1S,2R,5S)-4,4,8-TRIMETHYL-3-OXABICYCLO[3.3.1]NON-7-EN-2-YL]PHENOL'>T3O</scene>
|ACTIVITY=
|GENE= ESR1, ESR, NR3A1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Human Estrogen Receptor Alpha Ligand-Binding Domain In Complex With OBCP-1M-G and A Glucocorticoid Receptor Interacting Protein 1 NR Box II Peptide'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2G44 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=T3O:'>T3O</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G44 OCA].  
2G44 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2G44 OCA].  


==Reference==
==Reference==
Identification of ligands with bicyclic scaffolds provides insights into mechanisms of estrogen receptor subtype selectivity., Hsieh RW, Rajan SS, Sharma SK, Guo Y, DeSombre ER, Mrksich M, Greene GL, J Biol Chem. 2006 Jun 30;281(26):17909-19. Epub 2006 Apr 28. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16648639 16648639]
Identification of ligands with bicyclic scaffolds provides insights into mechanisms of estrogen receptor subtype selectivity., Hsieh RW, Rajan SS, Sharma SK, Guo Y, DeSombre ER, Mrksich M, Greene GL, J Biol Chem. 2006 Jun 30;281(26):17909-19. Epub 2006 Apr 28. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16648639 16648639]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: lbd]]
[[Category: lbd]]


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