3zmd: Difference between revisions
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[[ | ==Crystal structure of AbsC, a MarR family transcriptional regulator from Streptomyces coelicolor== | ||
<StructureSection load='3zmd' size='340' side='right' caption='[[3zmd]], [[Resolution|resolution]] 1.95Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[3zmd]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Streptomyces_coelicolor Streptomyces coelicolor]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZMD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3ZMD FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SAL:2-HYDROXYBENZOIC+ACID'>SAL</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3zmd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zmd OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3zmd RCSB], [http://www.ebi.ac.uk/pdbsum/3zmd PDBsum]</span></td></tr> | |||
</table> | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
Crystals of recombinant AbsC (subunit MW = 18 313 Da; 158 amino acids), a novel regulator of antibiotic production from Streptomyces coelicolor, were grown by vapour diffusion. The protein crystallizes in space group P2(1)2(1)2(1), with unit-cell parameters a = 43.53, b = 121.30, c = 143.75 A. Native data to a resolution of 2.25 A were recorded at station PX 14.1 (Daresbury) from a single crystal. Preliminary analysis of these data suggests that the asymmetric unit contains four copies of the AbsC monomer, giving an estimated solvent content of 47.0%. AbsC belongs to the MarR family of proteins that mediate ligand-responsive transcriptional control. | |||
Crystallization and preliminary X-ray analysis of AbsC, a novel regulator of antibiotic production in Streptomyces coelicolor.,Stevenson CE, Kock H, Mootien S, Davies SC, Bibb MJ, Lawson DM Acta Crystallogr Sect F Struct Biol Cryst Commun. 2007 Mar 1;63(Pt 3):233-5. Epub, 2007 Feb 23. PMID:17329821<ref>PMID:17329821</ref> | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
</div> | |||
== References == | |||
<references/> | |||
== | __TOC__ | ||
</StructureSection> | |||
[[Category: Streptomyces coelicolor]] | [[Category: Streptomyces coelicolor]] | ||
[[Category: Bibb, M J | [[Category: Bibb, M J]] | ||
[[Category: Davies, S C | [[Category: Davies, S C]] | ||
[[Category: Kock, H | [[Category: Kock, H]] | ||
[[Category: Lawson, D M | [[Category: Lawson, D M]] | ||
[[Category: Mootien, S | [[Category: Mootien, S]] | ||
[[Category: Stevenson, C E.M | [[Category: Stevenson, C E.M]] | ||
[[Category: Marr-family]] | [[Category: Marr-family]] | ||
[[Category: Transcription]] | [[Category: Transcription]] | ||
[[Category: Winged helix motif]] | [[Category: Winged helix motif]] | ||
Revision as of 09:04, 4 January 2015
Crystal structure of AbsC, a MarR family transcriptional regulator from Streptomyces coelicolor
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