4iy4: Difference between revisions
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==Structural and ligand binding properties of the Bateman domain of human magnesium transporters CNNM2 and CNNM4== | |||
<StructureSection load='4iy4' size='340' side='right' caption='[[4iy4]], [[Resolution|resolution]] 2.90Å' scene=''> | |||
== Structural highlights == | |||
==Disease== | <table><tr><td colspan='2'>[[4iy4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4IY4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4IY4 FirstGlance]. <br> | ||
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4iy0|4iy0]], [[4iy2|4iy2]], [[4iy3|4iy3]]</td></tr> | |||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CNNM2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4iy4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4iy4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4iy4 RCSB], [http://www.ebi.ac.uk/pdbsum/4iy4 PDBsum]</span></td></tr> | |||
</table> | |||
== Disease == | |||
[[http://www.uniprot.org/uniprot/CNNM2_HUMAN CNNM2_HUMAN]] Familial primary hypomagnesemia with normocalcuria and normocalcemia. The disease is caused by mutations affecting the gene represented in this entry. | [[http://www.uniprot.org/uniprot/CNNM2_HUMAN CNNM2_HUMAN]] Familial primary hypomagnesemia with normocalcuria and normocalcemia. The disease is caused by mutations affecting the gene represented in this entry. | ||
== Function == | |||
==Function== | |||
[[http://www.uniprot.org/uniprot/CNNM2_HUMAN CNNM2_HUMAN]] Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+) (By similarity). | [[http://www.uniprot.org/uniprot/CNNM2_HUMAN CNNM2_HUMAN]] Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+) (By similarity). | ||
__TOC__ | |||
</StructureSection> | |||
[[ | [[Category: Human]] | ||
[[Category: Accardi, A | [[Category: Accardi, A]] | ||
[[Category: Corral-Rodriguez, M A | [[Category: Corral-Rodriguez, M A]] | ||
[[Category: Diercks, T | [[Category: Diercks, T]] | ||
[[Category: Encinar, J A | [[Category: Encinar, J A]] | ||
[[Category: Ereno-Orbea, J | [[Category: Ereno-Orbea, J]] | ||
[[Category: Gomez-Garcia, I | [[Category: Gomez-Garcia, I]] | ||
[[Category: Martinez-Cruz, L A | [[Category: Martinez-Cruz, L A]] | ||
[[Category: Muller, D | [[Category: Muller, D]] | ||
[[Category: Oyenarte, I | [[Category: Oyenarte, I]] | ||
[[Category: Spiwok, V | [[Category: Spiwok, V]] | ||
[[Category: Stuiver, M | [[Category: Stuiver, M]] | ||
[[Category: Terashima, H | [[Category: Terashima, H]] | ||
[[Category: Bateman domain]] | [[Category: Bateman domain]] | ||
[[Category: Cbs domain]] | [[Category: Cbs domain]] | ||
