4gis: Difference between revisions
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[[ | ==crystal structure of an enolase family member from vibrio harveyi (efi-target 501692) with homology to mannonate dehydratase, with mg, glycerol and dicarboxylates bound (mixed loops, space group I4122)== | ||
<StructureSection load='4gis' size='340' side='right' caption='[[4gis]], [[Resolution|resolution]] 1.80Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[4gis]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibrio_harveyi Vibrio harveyi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GIS OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GIS FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MAE:MALEIC+ACID'>MAE</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MLA:MALONIC+ACID'>MLA</scene></td></tr> | |||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">VME_00770 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=669 Vibrio harveyi])</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gis FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gis OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4gis RCSB], [http://www.ebi.ac.uk/pdbsum/4gis PDBsum]</span></td></tr> | |||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/D0X4R4_VIBHA D0X4R4_VIBHA]] Has no detectable activity with D-mannonate and with a panel of 70 other acid sugars (in vitro), in spite of the conservation of the residues that are expected to be important for catalytic activity and cofactor binding. May have evolved a divergent function.<ref>PMID:24697546</ref> | |||
==See Also== | |||
*[[Enolase|Enolase]] | |||
== References == | |||
<references/> | |||
__TOC__ | |||
== | </StructureSection> | ||
[[Category: Vibrio harveyi]] | [[Category: Vibrio harveyi]] | ||
[[Category: Almo, S C | [[Category: Almo, S C]] | ||
[[Category: Bhosle, R | [[Category: Bhosle, R]] | ||
[[Category: Chowdhury, S | [[Category: Chowdhury, S]] | ||
[[Category: EFI, Enzyme Function Initiative | [[Category: EFI, Enzyme Function Initiative]] | ||
[[Category: Evans, B | [[Category: Evans, B]] | ||
[[Category: Gerlt, J A | [[Category: Gerlt, J A]] | ||
[[Category: Glenn, A Scott | [[Category: Glenn, A Scott]] | ||
[[Category: Hammonds, J | [[Category: Hammonds, J]] | ||
[[Category: Hillerich, B | [[Category: Hillerich, B]] | ||
[[Category: Imker, H J | [[Category: Imker, H J]] | ||
[[Category: Love, J | [[Category: Love, J]] | ||
[[Category: Morisco, L L | [[Category: Morisco, L L]] | ||
[[Category: Obaidi, N F.Al | [[Category: Obaidi, N F.Al]] | ||
[[Category: Seidel, R D | [[Category: Seidel, R D]] | ||
[[Category: Sojitra, S | [[Category: Sojitra, S]] | ||
[[Category: Toro, R | [[Category: Toro, R]] | ||
[[Category: Vetting, M W | [[Category: Vetting, M W]] | ||
[[Category: Washington, E | [[Category: Washington, E]] | ||
[[Category: Wasserman, S R | [[Category: Wasserman, S R]] | ||
[[Category: Efi]] | [[Category: Efi]] | ||
[[Category: Enolase]] | [[Category: Enolase]] | ||
