2h55: Difference between revisions

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[[Image:2h55.gif|left|200px]]<br /><applet load="2h55" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2h55.gif|left|200px]]
caption="2h55, resolution 2.00&Aring;" />
 
'''Structure of human Hsp90-alpha bound to the potent water soluble inhibitor PU-DZ8'''<br />
{{Structure
|PDB= 2h55 |SIZE=350|CAPTION= <scene name='initialview01'>2h55</scene>, resolution 2.00&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=DZ8:2-FLUORO-8-[(6-IODO-1,3-BENZODIOXOL-5-YL)METHYL]-9-[3-(ISOPROPYLAMINO)PROPYL]-9H-PURIN-6-AMINE'>DZ8</scene>
|ACTIVITY=
|GENE= HSPCA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Structure of human Hsp90-alpha bound to the potent water soluble inhibitor PU-DZ8'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2H55 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=DZ8:'>DZ8</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H55 OCA].  
2H55 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H55 OCA].  


==Reference==
==Reference==
Structural and quantum chemical studies of 8-aryl-sulfanyl adenine class Hsp90 inhibitors., Immormino RM, Kang Y, Chiosis G, Gewirth DT, J Med Chem. 2006 Aug 10;49(16):4953-60. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16884307 16884307]
Structural and quantum chemical studies of 8-aryl-sulfanyl adenine class Hsp90 inhibitors., Immormino RM, Kang Y, Chiosis G, Gewirth DT, J Med Chem. 2006 Aug 10;49(16):4953-60. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16884307 16884307]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: purine]]
[[Category: purine]]


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