2h62: Difference between revisions

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[[Image:2h62.gif|left|200px]]<br /><applet load="2h62" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2h62.gif|left|200px]]
caption="2h62, resolution 1.85&Aring;" />
 
'''Crystal structure of a ternary ligand-receptor complex of BMP-2'''<br />
{{Structure
|PDB= 2h62 |SIZE=350|CAPTION= <scene name='initialview01'>2h62</scene>, resolution 1.85&Aring;
|SITE=
|LIGAND=
|ACTIVITY= [http://en.wikipedia.org/wiki/Receptor_protein_serine/threonine_kinase Receptor protein serine/threonine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.30 2.7.11.30]
|GENE= BMP2, BMP2A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), BMPR1A, ACVRLK3, ALK3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), Acvr2b ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])
}}
 
'''Crystal structure of a ternary ligand-receptor complex of BMP-2'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2H62 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Active as [http://en.wikipedia.org/wiki/Receptor_protein_serine/threonine_kinase Receptor protein serine/threonine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.30 2.7.11.30] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H62 OCA].  
2H62 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2H62 OCA].  


==Reference==
==Reference==
A silent H-bond can be mutationally activated for high-affinity interaction of BMP-2 and activin type IIB receptor., Weber D, Kotzsch A, Nickel J, Harth S, Seher A, Mueller U, Sebald W, Mueller TD, BMC Struct Biol. 2007 Feb 12;7:6. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17295905 17295905]
A silent H-bond can be mutationally activated for high-affinity interaction of BMP-2 and activin type IIB receptor., Weber D, Kotzsch A, Nickel J, Harth S, Seher A, Mueller U, Sebald W, Mueller TD, BMC Struct Biol. 2007 Feb 12;7:6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17295905 17295905]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: tgf-beta superfamily]]
[[Category: tgf-beta superfamily]]


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