2hbu: Difference between revisions
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[[Image:2hbu.gif|left|200px]] | [[Image:2hbu.gif|left|200px]] | ||
'''Crystal structure of HIF prolyl hydroxylase EGLN-1 in complex with a biologically active inhibitor''' | {{Structure | ||
|PDB= 2hbu |SIZE=350|CAPTION= <scene name='initialview01'>2hbu</scene>, resolution 1.85Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=FE2:FE+(II)+ION'>FE2</scene> and <scene name='pdbligand=UN9:N-[(1-CHLORO-4-HYDROXYISOQUINOLIN-3-YL)CARBONYL]GLYCINE'>UN9</scene> | |||
|ACTIVITY= | |||
|GENE= EGLN1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | |||
}} | |||
'''Crystal structure of HIF prolyl hydroxylase EGLN-1 in complex with a biologically active inhibitor''' | |||
==Disease== | ==Disease== | ||
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==About this Structure== | ==About this Structure== | ||
2HBU is a [ | 2HBU is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HBU OCA]. | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: prolyl hydroxylase]] | [[Category: prolyl hydroxylase]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:15:08 2008'' | ||
Revision as of 15:15, 20 March 2008
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| 2hbu, resolution 1.85Å | |||||||||||||
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| Ligands: | FE2 and UN9 | ||||||||||||
| Gene: | EGLN1 (Homo sapiens) | ||||||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||||||
Crystal structure of HIF prolyl hydroxylase EGLN-1 in complex with a biologically active inhibitor
Disease
Known disease associated with this structure: Erythrocytosis, familial, 3 OMIM:[606425]
About this Structure
2HBU is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Thu Mar 20 17:15:08 2008
