2hej: Difference between revisions

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[[Image:2hej.gif|left|200px]]<br /><applet load="2hej" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2hej.gif|left|200px]]
caption="2hej, resolution 1.350&Aring;" />
 
'''Crystal structure of 17alpha-hydroxysteroid dehydrogenase in complex with NADP(H) in a closed conformation'''<br />
{{Structure
|PDB= 2hej |SIZE=350|CAPTION= <scene name='initialview01'>2hej</scene>, resolution 1.350&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene> and <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene>
|ACTIVITY=
|GENE= Akr1c21 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])
}}
 
'''Crystal structure of 17alpha-hydroxysteroid dehydrogenase in complex with NADP(H) in a closed conformation'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2HEJ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] with <scene name='pdbligand=NDP:'>NDP</scene>, <scene name='pdbligand=EDO:'>EDO</scene>, <scene name='pdbligand=BME:'>BME</scene> and <scene name='pdbligand=MPD:'>MPD</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HEJ OCA].  
2HEJ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HEJ OCA].  


==Reference==
==Reference==
Crystal structures of mouse 17alpha-hydroxysteroid dehydrogenase (apoenzyme and enzyme-NADP(H) binary complex): identification of molecular determinants responsible for the unique 17alpha-reductive activity of this enzyme., Faucher F, Pereira de Jesus-Tran K, Cantin L, Luu-The V, Labrie F, Breton R, J Mol Biol. 2006 Dec 8;364(4):747-63. Epub 2006 Sep 16. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17034817 17034817]
Crystal structures of mouse 17alpha-hydroxysteroid dehydrogenase (apoenzyme and enzyme-NADP(H) binary complex): identification of molecular determinants responsible for the unique 17alpha-reductive activity of this enzyme., Faucher F, Pereira de Jesus-Tran K, Cantin L, Luu-The V, Labrie F, Breton R, J Mol Biol. 2006 Dec 8;364(4):747-63. Epub 2006 Sep 16. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17034817 17034817]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: hydroxysteroid dehydrogenase]]
[[Category: hydroxysteroid dehydrogenase]]


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