2hp4: Difference between revisions

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[[Image:2hp4.jpg|left|200px]]<br /><applet load="2hp4" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2hp4.jpg|left|200px]]
caption="2hp4, resolution 2.10&Aring;" />
 
'''Computational design and crystal structure of an enhanced affinity mutant human CD8-alpha-alpha co-receptor'''<br />
{{Structure
|PDB= 2hp4 |SIZE=350|CAPTION= <scene name='initialview01'>2hp4</scene>, resolution 2.10&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
|ACTIVITY=
|GENE=
}}
 
'''Computational design and crystal structure of an enhanced affinity mutant human CD8-alpha-alpha co-receptor'''
 


==Overview==
==Overview==
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==Disease==
==Disease==
Known diseases associated with this structure: CD8 deficiency, familial OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=186910 186910]], Megakaryoblastic leukemia, acute OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606078 606078]]
Known disease associated with this structure: Megakaryoblastic leukemia, acute OMIM:[[http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=606078 606078]]


==About this Structure==
==About this Structure==
2HP4 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=SO4:'>SO4</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HP4 OCA].  
2HP4 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HP4 OCA].  


==Reference==
==Reference==
Computational design and crystal structure of an enhanced affinity mutant human CD8 alphaalpha coreceptor., Cole DK, Rizkallah PJ, Boulter JM, Sami M, Vuidepot AL, Glick M, Gao F, Bell JI, Jakobsen BK, Gao GF, Proteins. 2007 Apr 1;67(1):65-74. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17243170 17243170]
Computational design and crystal structure of an enhanced affinity mutant human CD8 alphaalpha coreceptor., Cole DK, Rizkallah PJ, Boulter JM, Sami M, Vuidepot AL, Glick M, Gao F, Bell JI, Jakobsen BK, Gao GF, Proteins. 2007 Apr 1;67(1):65-74. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17243170 17243170]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: soluble protein]]
[[Category: soluble protein]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:44:09 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:19:44 2008''
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