2hre: Difference between revisions

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[[Image:2hre.jpg|left|200px]]<br /><applet load="2hre" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2hre.jpg|left|200px]]
caption="2hre, resolution 2.50&Aring;" />
 
'''Structure of human ferrochelatase variant E343K with protoporphyrin IX bound'''<br />
{{Structure
|PDB= 2hre |SIZE=350|CAPTION= <scene name='initialview01'>2hre</scene>, resolution 2.50&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=PP9:PROTOPORPHYRIN+IX'>PP9</scene>, <scene name='pdbligand=CHD:CHOLIC+ACID'>CHD</scene> and <scene name='pdbligand=FES:FE2/S2 (INORGANIC) CLUSTER'>FES</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Ferrochelatase Ferrochelatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.99.1.1 4.99.1.1]
|GENE= FECH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Structure of human ferrochelatase variant E343K with protoporphyrin IX bound'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2HRE is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=PP9:'>PP9</scene>, <scene name='pdbligand=CHD:'>CHD</scene> and <scene name='pdbligand=FES:'>FES</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Ferrochelatase Ferrochelatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.99.1.1 4.99.1.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HRE OCA].  
2HRE is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HRE OCA].  


==Reference==
==Reference==
Substrate interactions with human ferrochelatase., Medlock A, Swartz L, Dailey TA, Dailey HA, Lanzilotta WN, Proc Natl Acad Sci U S A. 2007 Feb 6;104(6):1789-93. Epub 2007 Jan 29. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17261801 17261801]
Substrate interactions with human ferrochelatase., Medlock A, Swartz L, Dailey TA, Dailey HA, Lanzilotta WN, Proc Natl Acad Sci U S A. 2007 Feb 6;104(6):1789-93. Epub 2007 Jan 29. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17261801 17261801]
[[Category: Ferrochelatase]]
[[Category: Ferrochelatase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: protoporphyrin ix]]
[[Category: protoporphyrin ix]]


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