2huo: Difference between revisions

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[[Image:2huo.gif|left|200px]]<br /><applet load="2huo" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2huo.gif|left|200px]]
caption="2huo, resolution 2.00&Aring;" />
 
'''Crystal structure of mouse myo-inositol oxygenase in complex with substrate'''<br />
{{Structure
|PDB= 2huo |SIZE=350|CAPTION= <scene name='initialview01'>2huo</scene>, resolution 2.00&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=OH:HYDROXIDE+ION'>OH</scene>, <scene name='pdbligand=INS:1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE'>INS</scene> and <scene name='pdbligand=FMT:FORMIC ACID'>FMT</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Inositol_oxygenase Inositol oxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.13.99.1 1.13.99.1]
|GENE= Miox, Aldrl6, Rsor ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])
}}
 
'''Crystal structure of mouse myo-inositol oxygenase in complex with substrate'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2HUO is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] with <scene name='pdbligand=FE:'>FE</scene>, <scene name='pdbligand=OH:'>OH</scene>, <scene name='pdbligand=INS:'>INS</scene> and <scene name='pdbligand=FMT:'>FMT</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Inositol_oxygenase Inositol oxygenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.13.99.1 1.13.99.1] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HUO OCA].  
2HUO is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HUO OCA].  


==Reference==
==Reference==
Crystal structure of a substrate complex of myo-inositol oxygenase, a di-iron oxygenase with a key role in inositol metabolism., Brown PM, Caradoc-Davies TT, Dickson JM, Cooper GJ, Loomes KM, Baker EN, Proc Natl Acad Sci U S A. 2006 Oct 10;103(41):15032-7. Epub 2006 Sep 29. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17012379 17012379]
Crystal structure of a substrate complex of myo-inositol oxygenase, a di-iron oxygenase with a key role in inositol metabolism., Brown PM, Caradoc-Davies TT, Dickson JM, Cooper GJ, Loomes KM, Baker EN, Proc Natl Acad Sci U S A. 2006 Oct 10;103(41):15032-7. Epub 2006 Sep 29. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17012379 17012379]
[[Category: Inositol oxygenase]]
[[Category: Inositol oxygenase]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: protein-substrate complex]]
[[Category: protein-substrate complex]]


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