2hxm: Difference between revisions

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[[Image:2hxm.gif|left|200px]]<br /><applet load="2hxm" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2hxm.gif|left|200px]]
caption="2hxm, resolution 1.30&Aring;" />
 
'''Complex of UNG2 and a small Molecule synthetic Inhibitor'''<br />
{{Structure
|PDB= 2hxm |SIZE=350|CAPTION= <scene name='initialview01'>2hxm</scene>, resolution 1.30&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=302:4-[(1E,7E)-8-(2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDIN-4-YL)-3,6-DIOXA-2,7-DIAZAOCTA-1,7-DIEN-1-YL]BENZOIC ACID'>302</scene>
|ACTIVITY=
|GENE= UNG, DGU, UNG15 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''Complex of UNG2 and a small Molecule synthetic Inhibitor'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2HXM is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=302:'>302</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HXM OCA].  
2HXM is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2HXM OCA].  


==Reference==
==Reference==
Mimicking damaged DNA with a small molecule inhibitor of human UNG2., Krosky DJ, Bianchet MA, Seiple L, Chung S, Amzel LM, Stivers JT, Nucleic Acids Res. 2006;34(20):5872-9. Epub 2006 Oct 24. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17062624 17062624]
Mimicking damaged DNA with a small molecule inhibitor of human UNG2., Krosky DJ, Bianchet MA, Seiple L, Chung S, Amzel LM, Stivers JT, Nucleic Acids Res. 2006;34(20):5872-9. Epub 2006 Oct 24. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17062624 17062624]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: uracil dna glycosylase]]
[[Category: uracil dna glycosylase]]


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