2i17: Difference between revisions

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[[Image:2i17.gif|left|200px]]<br /><applet load="2i17" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2i17.gif|left|200px]]
caption="2i17, resolution 0.81&Aring;" />
 
'''Human aldose reductase in complex with NADP+ and the inhibitor IDD594 at temperature of 60K'''<br />
{{Structure
|PDB= 2i17 |SIZE=350|CAPTION= <scene name='initialview01'>2i17</scene>, resolution 0.81&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=NDP:NADPH+DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NDP</scene>, <scene name='pdbligand=LDT:IDD594'>LDT</scene> and <scene name='pdbligand=CIT:CITRIC ACID'>CIT</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Aldehyde_reductase Aldehyde reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.21 1.1.1.21]
|GENE=
}}
 
'''Human aldose reductase in complex with NADP+ and the inhibitor IDD594 at temperature of 60K'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2I17 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NDP:'>NDP</scene>, <scene name='pdbligand=LDT:'>LDT</scene> and <scene name='pdbligand=CIT:'>CIT</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Aldehyde_reductase Aldehyde reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.21 1.1.1.21] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I17 OCA].  
2I17 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I17 OCA].  


==Reference==
==Reference==
Ultrahigh-resolution study of protein atomic displacement parameters at cryotemperatures obtained with a helium cryostat., Petrova T, Ginell S, Mitschler A, Hazemann I, Schneider T, Cousido A, Lunin VY, Joachimiak A, Podjarny A, Acta Crystallogr D Biol Crystallogr. 2006 Dec;62(Pt 12):1535-44. Epub 2006, Nov 23. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17139089 17139089]
Ultrahigh-resolution study of protein atomic displacement parameters at cryotemperatures obtained with a helium cryostat., Petrova T, Ginell S, Mitschler A, Hazemann I, Schneider T, Cousido A, Lunin VY, Joachimiak A, Podjarny A, Acta Crystallogr D Biol Crystallogr. 2006 Dec;62(Pt 12):1535-44. Epub 2006, Nov 23. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17139089 17139089]
[[Category: Aldehyde reductase]]
[[Category: Aldehyde reductase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: oxidoreductase]]
[[Category: oxidoreductase]]


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