2i6e: Difference between revisions
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'''Crystal structure of protein DR0370 from Deinococcus radiodurans, Pfam DUF178''' | {{Structure | ||
|PDB= 2i6e |SIZE=350|CAPTION= <scene name='initialview01'>2i6e</scene>, resolution 2.50Å | |||
|SITE= | |||
|LIGAND= <scene name='pdbligand=SO4:SULFATE ION'>SO4</scene> | |||
|ACTIVITY= | |||
|GENE= DR_0370 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1299 Deinococcus radiodurans]) | |||
}} | |||
'''Crystal structure of protein DR0370 from Deinococcus radiodurans, Pfam DUF178''' | |||
==Overview== | ==Overview== | ||
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==About this Structure== | ==About this Structure== | ||
2I6E is a [ | 2I6E is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Deinococcus_radiodurans Deinococcus radiodurans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I6E OCA]. | ||
==Reference== | ==Reference== | ||
X-ray structures of two proteins belonging to Pfam DUF178 revealed unexpected structural similarity to the DUF191 Pfam family., Tyagi R, Burley SK, Swaminathan S, BMC Struct Biol. 2007 Oct 1;7:62. PMID:[http:// | X-ray structures of two proteins belonging to Pfam DUF178 revealed unexpected structural similarity to the DUF191 Pfam family., Tyagi R, Burley SK, Swaminathan S, BMC Struct Biol. 2007 Oct 1;7:62. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17908300 17908300] | ||
[[Category: Deinococcus radiodurans]] | [[Category: Deinococcus radiodurans]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: protein structure initiative]] | [[Category: protein structure initiative]] | ||
[[Category: psi-2]] | [[Category: psi-2]] | ||
[[Category: structural | [[Category: structural genomic]] | ||
[[Category: unknown function]] | [[Category: unknown function]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:25:58 2008'' | ||
Revision as of 15:25, 20 March 2008
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| 2i6e, resolution 2.50Å | |||||||||||||
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| Ligands: | SO4 | ||||||||||||
| Gene: | DR_0370 (Deinococcus radiodurans) | ||||||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||||||
Crystal structure of protein DR0370 from Deinococcus radiodurans, Pfam DUF178
Overview
BACKGROUND: Pfam is a comprehensive collection of protein domains and families, with a range of well-established information including genome annotation. Pfam has two large series of functionally uncharacterized families, known as Domains of Unknown Function (DUFs) and Uncharacterized Protein Families (UPFs). RESULTS: Crystal structures of two proteins from Deinococcus radiodurans and Streptomyces coelicolor belonging to Pfam protein family DUF178 (ID: PF02621) have been determined using Selenium-Single-wavelength Anomalous Dispersion (Se-SAD). Based on the structure, we have identified the putative function for this family of protein. CONCLUSION: Unexpectedly, we found that DUF178 Pfam is remarkably similar to Pfam family DUF191 suggesting that the sequence-based classification alone may not be sufficient to classify proteins into Pfam families.
About this Structure
2I6E is a Single protein structure of sequence from Deinococcus radiodurans. Full crystallographic information is available from OCA.
Reference
X-ray structures of two proteins belonging to Pfam DUF178 revealed unexpected structural similarity to the DUF191 Pfam family., Tyagi R, Burley SK, Swaminathan S, BMC Struct Biol. 2007 Oct 1;7:62. PMID:17908300
Page seeded by OCA on Thu Mar 20 17:25:58 2008
Proteopedia Page Contributors and Editors (what is this?)
- Pages with broken file links
- Deinococcus radiodurans
- Single protein
- Burley, S K.
- Kumaran, D.
- NYSGXRC, New York Structural GenomiX Research Consortium.
- Swaminathan, S.
- Tyagi, R.
- SO4
- 10093b
- Hypothetical protein
- New york structural genomix research consortium
- Nysgxrc
- Pfam:duf178
- Protein structure initiative
- Psi-2
- Structural genomic
- Unknown function
