2i6k: Difference between revisions

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[[Image:2i6k.jpg|left|200px]]<br /><applet load="2i6k" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2i6k.jpg|left|200px]]
caption="2i6k, resolution 2.00&Aring;" />
 
'''Crystal structure of human type I IPP isomerase complexed with a substrate analog'''<br />
{{Structure
|PDB= 2i6k |SIZE=350|CAPTION= <scene name='initialview01'>2i6k</scene>, resolution 2.00&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=EA2:AMINOETHANOLPYROPHOSPHATE'>EA2</scene> and <scene name='pdbligand=ACY:ACETIC ACID'>ACY</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Isopentenyl-diphosphate_Delta-isomerase Isopentenyl-diphosphate Delta-isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.3.2 5.3.3.2]
|GENE=
}}
 
'''Crystal structure of human type I IPP isomerase complexed with a substrate analog'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2I6K is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=MN:'>MN</scene>, <scene name='pdbligand=MG:'>MG</scene>, <scene name='pdbligand=EA2:'>EA2</scene> and <scene name='pdbligand=ACY:'>ACY</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Isopentenyl-diphosphate_Delta-isomerase Isopentenyl-diphosphate Delta-isomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.3.3.2 5.3.3.2] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I6K OCA].  
2I6K is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2I6K OCA].  


==Reference==
==Reference==
Crystal structures of human IPP isomerase: new insights into the catalytic mechanism., Zhang C, Liu L, Xu H, Wei Z, Wang Y, Lin Y, Gong W, J Mol Biol. 2007 Mar 9;366(5):1437-46. Epub 2006 Nov 3. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17137593 17137593]
Crystal structures of human IPP isomerase: new insights into the catalytic mechanism., Zhang C, Liu L, Xu H, Wei Z, Wang Y, Lin Y, Gong W, J Mol Biol. 2007 Mar 9;366(5):1437-46. Epub 2006 Nov 3. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17137593 17137593]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Isopentenyl-diphosphate Delta-isomerase]]
[[Category: Isopentenyl-diphosphate Delta-isomerase]]
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[[Category: globular domain]]
[[Category: globular domain]]


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