2iaj: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,615 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,615 edits
No edit summary
Line 1: Line 1:
[[Image:2iaj.gif|left|200px]]<br /><applet load="2iaj" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2iaj.gif|left|200px]]
caption="2iaj, resolution 2.500&Aring;" />
 
'''Crystal Structure of K103N/Y181C Mutant HIV-1 Reverse Transcriptase (RT) in Complex with ATP'''<br />
{{Structure
|PDB= 2iaj |SIZE=350|CAPTION= <scene name='initialview01'>2iaj</scene>, resolution 2.500&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ATP:ADENOSINE-5'-TRIPHOSPHATE'>ATP</scene> and <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/RNA-directed_DNA_polymerase RNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.49 2.7.7.49]
|GENE= pol ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 Human immunodeficiency virus 1])
}}
 
'''Crystal Structure of K103N/Y181C Mutant HIV-1 Reverse Transcriptase (RT) in Complex with ATP'''
 


==Overview==
==Overview==
Line 7: Line 16:


==About this Structure==
==About this Structure==
2IAJ is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1] with <scene name='pdbligand=MN:'>MN</scene>, <scene name='pdbligand=NA:'>NA</scene>, <scene name='pdbligand=ATP:'>ATP</scene> and <scene name='pdbligand=GOL:'>GOL</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/RNA-directed_DNA_polymerase RNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.49 2.7.7.49] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IAJ OCA].  
2IAJ is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Human_immunodeficiency_virus_1 Human immunodeficiency virus 1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IAJ OCA].  


==Reference==
==Reference==
Crystal structures of clinically relevant Lys103Asn/Tyr181Cys double mutant HIV-1 reverse transcriptase in complexes with ATP and non-nucleoside inhibitor HBY 097., Das K, Sarafianos SG, Clark AD Jr, Boyer PL, Hughes SH, Arnold E, J Mol Biol. 2007 Jan 5;365(1):77-89. Epub 2006 Sep 15. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17056061 17056061]
Crystal structures of clinically relevant Lys103Asn/Tyr181Cys double mutant HIV-1 reverse transcriptase in complexes with ATP and non-nucleoside inhibitor HBY 097., Das K, Sarafianos SG, Clark AD Jr, Boyer PL, Hughes SH, Arnold E, J Mol Biol. 2007 Jan 5;365(1):77-89. Epub 2006 Sep 15. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17056061 17056061]
[[Category: Human immunodeficiency virus 1]]
[[Category: Human immunodeficiency virus 1]]
[[Category: Protein complex]]
[[Category: Protein complex]]
Line 20: Line 29:
[[Category: MN]]
[[Category: MN]]
[[Category: NA]]
[[Category: NA]]
[[Category: aids]]
[[Category: aid]]
[[Category: atp]]
[[Category: atp]]
[[Category: dna polymerization]]
[[Category: dna polymerization]]
Line 30: Line 39:
[[Category: rt]]
[[Category: rt]]


''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:50:43 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:27:11 2008''
Retrieved from "https://proteopedia.org/2iaj"