2icf: Difference between revisions

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[[Image:2icf.gif|left|200px]]<br /><applet load="2icf" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2icf.gif|left|200px]]
caption="2icf, resolution 4.10&Aring;" />
 
'''CRIg bound to C3b'''<br />
{{Structure
|PDB= 2icf |SIZE=350|CAPTION= <scene name='initialview01'>2icf</scene>, resolution 4.10&Aring;
|SITE= <scene name='pdbsite=AC1:Nag+Binding+Site+For+Residue+A+643'>AC1</scene>, <scene name='pdbsite=AC2:Nag+Binding+Site+For+Residue+A+644'>AC2</scene>, <scene name='pdbsite=AC3:Bma+Binding+Site+For+Residue+A+645'>AC3</scene>, <scene name='pdbsite=AC4:Nag+Binding+Site+For+Residue+B+5'>AC4</scene> and <scene name='pdbsite=AC5:Ca+Binding+Site+For+Residue+A+647'>AC5</scene>
|LIGAND= <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene> and <scene name='pdbligand=CA:CALCIUM ION'>CA</scene>
|ACTIVITY=
|GENE=
}}
 
'''CRIg bound to C3b'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2ICF is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=NAG:'>NAG</scene> and <scene name='pdbligand=CA:'>CA</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Known structural/functional Sites: <scene name='pdbsite=AC1:Nag+Binding+Site+For+Residue+A+643'>AC1</scene>, <scene name='pdbsite=AC2:Nag+Binding+Site+For+Residue+A+644'>AC2</scene>, <scene name='pdbsite=AC3:Bma+Binding+Site+For+Residue+A+645'>AC3</scene>, <scene name='pdbsite=AC4:Nag+Binding+Site+For+Residue+B+5'>AC4</scene> and <scene name='pdbsite=AC5:Ca+Binding+Site+For+Residue+A+647'>AC5</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ICF OCA].  
2ICF is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ICF OCA].  


==Reference==
==Reference==
Structure of C3b in complex with CRIg gives insights into regulation of complement activation., Wiesmann C, Katschke KJ, Yin J, Helmy KY, Steffek M, Fairbrother WJ, McCallum SA, Embuscado L, DeForge L, Hass PE, van Lookeren Campagne M, Nature. 2006 Nov 9;444(7116):217-20. Epub 2006 Oct 15. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17051150 17051150]
Structure of C3b in complex with CRIg gives insights into regulation of complement activation., Wiesmann C, Katschke KJ, Yin J, Helmy KY, Steffek M, Fairbrother WJ, McCallum SA, Embuscado L, DeForge L, Hass PE, van Lookeren Campagne M, Nature. 2006 Nov 9;444(7116):217-20. Epub 2006 Oct 15. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17051150 17051150]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: immune system]]
[[Category: immune system]]


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