2ihm: Difference between revisions

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[[Image:2ihm.gif|left|200px]]<br /><applet load="2ihm" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2ihm.gif|left|200px]]
caption="2ihm, resolution 2.4&Aring;" />
 
'''Polymerase mu in ternary complex with gapped 11mer DNA duplex and bound incoming nucleotide'''<br />
{{Structure
|PDB= 2ihm |SIZE=350|CAPTION= <scene name='initialview01'>2ihm</scene>, resolution 2.4&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene> and <scene name='pdbligand=D3T:2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE'>D3T</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7]
|GENE= Polm ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 Mus musculus])
}}
 
'''Polymerase mu in ternary complex with gapped 11mer DNA duplex and bound incoming nucleotide'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2IHM is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] with <scene name='pdbligand=MG:'>MG</scene>, <scene name='pdbligand=NA:'>NA</scene> and <scene name='pdbligand=D3T:'>D3T</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IHM OCA].  
2IHM is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IHM OCA].  


==Reference==
==Reference==
Structural insight into the substrate specificity of DNA Polymerase mu., Moon AF, Garcia-Diaz M, Bebenek K, Davis BJ, Zhong X, Ramsden DA, Kunkel TA, Pedersen LC, Nat Struct Mol Biol. 2007 Jan;14(1):45-53. Epub 2006 Dec 10. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17159995 17159995]
Structural insight into the substrate specificity of DNA Polymerase mu., Moon AF, Garcia-Diaz M, Bebenek K, Davis BJ, Zhong X, Ramsden DA, Kunkel TA, Pedersen LC, Nat Struct Mol Biol. 2007 Jan;14(1):45-53. Epub 2006 Dec 10. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17159995 17159995]
[[Category: DNA-directed DNA polymerase]]
[[Category: DNA-directed DNA polymerase]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
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[[Category: polymerase]]
[[Category: polymerase]]


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