2ipk: Difference between revisions

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[[Image:2ipk.gif|left|200px]]~~<br /><applet load~~="2ipk~~" size~~="350~~" color~~=~~"white" frame~~=~~"true" align="right" spinBox="true"~~

[[Image:2ipk.gif|left|200px]]

~~caption="~~2ipk, resolution 2.300Å" />

'''Crystal Structure of the MHC Class II Molecule HLA-DR1 in Complex with the Fluorogenic Peptide, AcPKXVKQNTLKLAT (X=3-[5-(dimethylamino)-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl]-L-alanine) and the Superantigen, SEC3 Variant 3B2'''~~<br />~~

{{Structure

|PDB= 2ipk |SIZE=350|CAPTION= <scene name='initialview01'>2ipk</scene>, resolution 2.300Å

|SITE=

|LIGAND=

|ACTIVITY=

|GENE= HLA-DRA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), HLA-DRB1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), entC3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 Staphylococcus aureus])

}}

'''Crystal Structure of the MHC Class II Molecule HLA-DR1 in Complex with the Fluorogenic Peptide, AcPKXVKQNTLKLAT (X=3-[5-(dimethylamino)-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl]-L-alanine) and the Superantigen, SEC3 Variant 3B2'''

==Overview==

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==About this Structure==

2IPK is a [~~http://en.wikipedia.org/wiki/Protein_complex~~ Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IPK OCA].

2IPK is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IPK OCA].

==Reference==

Fluorogenic probes for monitoring peptide binding to class II MHC proteins in living cells., Venkatraman P, Nguyen TT, Sainlos M, Bilsel O, Chitta S, Imperiali B, Stern LJ, Nat Chem Biol. 2007 Apr;3(4):222-8. Epub 2007 Mar 11. PMID:[http://~~ispc~~.~~weizmann~~.ac.~~il/~~/~~pmbin~~/~~getpm?pmid=~~17351628 17351628]

Fluorogenic probes for monitoring peptide binding to class II MHC proteins in living cells., Venkatraman P, Nguyen TT, Sainlos M, Bilsel O, Chitta S, Imperiali B, Stern LJ, Nat Chem Biol. 2007 Apr;3(4):222-8. Epub 2007 Mar 11. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17351628 17351628]

[[Category: Homo sapiens]]

[[Category: Protein complex]]

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[[Category: sec3]]

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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:32:07 2008''

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@@ Line 1: / Line 1: @@
-[[Image:2ipk.gif|left|200px]]<br /><applet load="2ipk" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:2ipk.gif|left|200px]]
-caption="2ipk, resolution 2.300&Aring;" />
-'''Crystal Structure of the MHC Class II Molecule HLA-DR1 in Complex with the Fluorogenic Peptide, AcPKXVKQNTLKLAT (X=3-[5-(dimethylamino)-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl]-L-alanine) and the Superantigen, SEC3 Variant 3B2'''<br />
+ {{Structure
+|PDB= 2ipk |SIZE=350|CAPTION= <scene name='initialview01'>2ipk</scene>, resolution 2.300&Aring;
+|SITE=
+|LIGAND=
+|ACTIVITY=
+|GENE= HLA-DRA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), HLA-DRB1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), entC3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 Staphylococcus aureus])
+}}
+'''Crystal Structure of the MHC Class II Molecule HLA-DR1 in Complex with the Fluorogenic Peptide, AcPKXVKQNTLKLAT (X=3-[5-(dimethylamino)-1,3-dioxo-1,3-dihydro-2H-isoindol-2-yl]-L-alanine) and the Superantigen, SEC3 Variant 3B2'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-IPK is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IPK OCA].
+IPK is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IPK OCA].
 ==Reference==
-Fluorogenic probes for monitoring peptide binding to class II MHC proteins in living cells., Venkatraman P, Nguyen TT, Sainlos M, Bilsel O, Chitta S, Imperiali B, Stern LJ, Nat Chem Biol. 2007 Apr;3(4):222-8. Epub 2007 Mar 11. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17351628 17351628]
+Fluorogenic probes for monitoring peptide binding to class II MHC proteins in living cells., Venkatraman P, Nguyen TT, Sainlos M, Bilsel O, Chitta S, Imperiali B, Stern LJ, Nat Chem Biol. 2007 Apr;3(4):222-8. Epub 2007 Mar 11. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17351628 17351628]
 [[Category: Homo sapiens]]
 [[Category: Protein complex]]
@@ Line 26: / Line 35: @@
 [[Category: sec3]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 17:54:52 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:32:07 2008''