1wlp: Difference between revisions

== Structural highlights ==

<table><tr><td colspan='2'>[[1wlp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WLP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1WLP FirstGlance]. <br>

== Disease ==

[[http://www.uniprot.org/uniprot/CY24A_HUMAN CY24A_HUMAN]] Defects in CYBA are a cause of chronic granulomatous disease autosomal recessive cytochrome-b-negative (ARCGD) [MIM:[http://omim.org/entry/233690 233690]]. Chronic granulomatous disease is a genetically heterogeneous disorder characterized by the inability of neutrophils and phagocytes to kill microbes that they have ingested. Patients suffer from life-threatening bacterial/fungal infections.<ref>PMID:2243141</ref> <ref>PMID:1415254</ref> <ref>PMID:1763037</ref> <ref>PMID:8168815</ref> <ref>PMID:7964505</ref> <ref>PMID:10910929</ref> <ref>PMID:10759707</ref> <ref>PMID:10914676</ref> <ref>PMID:18422995</ref>  [[http://www.uniprot.org/uniprot/NCF1_HUMAN NCF1_HUMAN]] Defects in NCF1 are the cause of chronic granulomatous disease autosomal recessive cytochrome-b-positive type 1 (CGD1) [MIM:[http://omim.org/entry/233700 233700]]. Chronic granulomatous disease is a genetically heterogeneous disorder characterized by the inability of neutrophils and phagocytes to kill microbes that they have ingested. Patients suffer from life-threatening bacterial/fungal infections.<ref>PMID:2011585</ref> <ref>PMID:11133775</ref>   

</StructureSection>

[[Category: Homo sapiens]]

[[Category: Oxidoreductase-signaling protein complex]]

[[Category: Polyproline]]

[[Category: Sh3 domain]]