1u59: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[1u59]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U59 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1U59 FirstGlance]. <br> | <table><tr><td colspan='2'>[[1u59]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U59 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1U59 FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=STU:STAUROSPORINE'>STU</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=STU:STAUROSPORINE'>STU</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ZAP70, SRK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ZAP70, SRK ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])</td></tr> | ||
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 and 2.7.10.2 2.7.10.1 and 2.7.10.2] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Transferase Transferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 and 2.7.10.2 2.7.10.1 and 2.7.10.2] </span></td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1u59 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u59 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1u59 RCSB], [http://www.ebi.ac.uk/pdbsum/1u59 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1u59 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u59 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1u59 RCSB], [http://www.ebi.ac.uk/pdbsum/1u59 PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Disease == | == Disease == | ||
[[http://www.uniprot.org/uniprot/ZAP70_HUMAN ZAP70_HUMAN]] Defects in ZAP70 are the cause of selective T-cell defect (STCD) [MIM:[http://omim.org/entry/269840 269840]]. A form of severe combined immunodeficiency characterized by a selective absence of CD8+ T cells.<ref>PMID:8124727</ref> <ref>PMID:8202713</ref> <ref>PMID:11412303</ref> <ref>PMID:11123350</ref> <ref>PMID:18509675</ref> | [[http://www.uniprot.org/uniprot/ZAP70_HUMAN ZAP70_HUMAN]] Defects in ZAP70 are the cause of selective T-cell defect (STCD) [MIM:[http://omim.org/entry/269840 269840]]. A form of severe combined immunodeficiency characterized by a selective absence of CD8+ T cells.<ref>PMID:8124727</ref> <ref>PMID:8202713</ref> <ref>PMID:11412303</ref> <ref>PMID:11123350</ref> <ref>PMID:18509675</ref> | ||
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[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
[[Category: Babine, R E | [[Category: Babine, R E]] | ||
[[Category: Cantin, S M | [[Category: Cantin, S M]] | ||
[[Category: Gorga, J C | [[Category: Gorga, J C]] | ||
[[Category: Jin, L | [[Category: Jin, L]] | ||
[[Category: Pandey, P | [[Category: Pandey, P]] | ||
[[Category: Petrella, E C | [[Category: Petrella, E C]] | ||
[[Category: Pluskey, S | [[Category: Pluskey, S]] | ||
[[Category: Rynkiewicz, M J | [[Category: Rynkiewicz, M J]] | ||
[[Category: Seidl, K J | [[Category: Seidl, K J]] | ||
[[Category: Strickler, J E | [[Category: Strickler, J E]] | ||
[[Category: Weaver, D T | [[Category: Weaver, D T]] | ||
