2ixu: Difference between revisions

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[[Image:2ixu.jpg|left|200px]]<br /><applet load="2ixu" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2ixu.jpg|left|200px]]
caption="2ixu, resolution 2.28&Aring;" />
 
'''CRYSTAL STRUCTURE OF THE MODULAR CPL-1 ENDOLYSIN COMPLEXED WITH A PEPTIDOGLYCAN ANALOGUE (WILD-TYPE ENDOLYSIN)'''<br />
{{Structure
|PDB= 2ixu |SIZE=350|CAPTION= <scene name='initialview01'>2ixu</scene>, resolution 2.28&Aring;
|SITE= <scene name='pdbsite=AC1:Fmt+Binding+Site+For+Chain+A'>AC1</scene>
|LIGAND= <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=MU2:N-ACETYLMURAMYL-L-ALANYL-D-ISOGLUTAMINE'>MU2</scene> and <scene name='pdbligand=FMT:FORMIC ACID'>FMT</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17]
|GENE=
}}
 
'''CRYSTAL STRUCTURE OF THE MODULAR CPL-1 ENDOLYSIN COMPLEXED WITH A PEPTIDOGLYCAN ANALOGUE (WILD-TYPE ENDOLYSIN)'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2IXU is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Streptococcus_phage_cp-1 Streptococcus phage cp-1] with <scene name='pdbligand=NAG:'>NAG</scene>, <scene name='pdbligand=MU2:'>MU2</scene> and <scene name='pdbligand=FMT:'>FMT</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] Known structural/functional Site: <scene name='pdbsite=AC1:Fmt+Binding+Site+For+Chain+A'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IXU OCA].  
2IXU is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptococcus_phage_cp-1 Streptococcus phage cp-1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2IXU OCA].  


==Reference==
==Reference==
Elucidation of the molecular recognition of bacterial cell wall by modular pneumococcal phage endolysin CPL-1., Perez-Dorado I, Campillo NE, Monterroso B, Hesek D, Lee M, Paez JA, Garcia P, Martinez-Ripoll M, Garcia JL, Mobashery S, Menendez M, Hermoso JA, J Biol Chem. 2007 Aug 24;282(34):24990-9. Epub 2007 Jun 19. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17581815 17581815]
Elucidation of the molecular recognition of bacterial cell wall by modular pneumococcal phage endolysin CPL-1., Perez-Dorado I, Campillo NE, Monterroso B, Hesek D, Lee M, Paez JA, Garcia P, Martinez-Ripoll M, Garcia JL, Mobashery S, Menendez M, Hermoso JA, J Biol Chem. 2007 Aug 24;282(34):24990-9. Epub 2007 Jun 19. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17581815 17581815]
[[Category: Lysozyme]]
[[Category: Lysozyme]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: pneumococcal cell wall degradation]]
[[Category: pneumococcal cell wall degradation]]


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