2j0x: Difference between revisions

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[[Image:2j0x.gif|left|200px]]<br /><applet load="2j0x" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2j0x.gif|left|200px]]
caption="2j0x, resolution 2.80&Aring;" />
 
'''CRYSTAL STRUCTURE OF E. COLI ASPARTOKINASE III IN COMPLEX WITH LYSINE AND ASPARTATE (T-STATE)'''<br />
{{Structure
|PDB= 2j0x |SIZE=350|CAPTION= <scene name='initialview01'>2j0x</scene>, resolution 2.80&Aring;
|SITE= <scene name='pdbsite=AC1:Po4+Binding+Site+For+Chain+A'>AC1</scene>
|LIGAND= <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ASP:ASPARTIC+ACID'>ASP</scene> and <scene name='pdbligand=LYS:LYSINE'>LYS</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Aspartate_kinase Aspartate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.2.4 2.7.2.4]
|GENE=
}}
 
'''CRYSTAL STRUCTURE OF E. COLI ASPARTOKINASE III IN COMPLEX WITH LYSINE AND ASPARTATE (T-STATE)'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2J0X is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=PO4:'>PO4</scene>, <scene name='pdbligand=ASP:'>ASP</scene> and <scene name='pdbligand=LYS:'>LYS</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Aspartate_kinase Aspartate kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.2.4 2.7.2.4] Known structural/functional Site: <scene name='pdbsite=AC1:Po4+Binding+Site+For+Chain+A'>AC1</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J0X OCA].  
2J0X is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J0X OCA].  


==Reference==
==Reference==
Structures of R- and T-state Escherichia coli aspartokinase III. Mechanisms of the allosteric transition and inhibition by lysine., Kotaka M, Ren J, Lockyer M, Hawkins AR, Stammers DK, J Biol Chem. 2006 Oct 20;281(42):31544-52. Epub 2006 Aug 12. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=16905770 16905770]
Structures of R- and T-state Escherichia coli aspartokinase III. Mechanisms of the allosteric transition and inhibition by lysine., Kotaka M, Ren J, Lockyer M, Hawkins AR, Stammers DK, J Biol Chem. 2006 Oct 20;281(42):31544-52. Epub 2006 Aug 12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16905770 16905770]
[[Category: Aspartate kinase]]
[[Category: Aspartate kinase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: transferase]]
[[Category: transferase]]


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