Sandbox Reserved 951: Difference between revisions
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==Biological role== | ==Biological role== | ||
=== The different reactions=== | === The different reactions=== | ||
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=====Luciferin & Coenzyme A===== | =====Luciferin & Coenzyme A===== | ||
It has been found that the reaction between luciferin and CoA is possible, forming in a first step luciferin-AMP and then luciferin-CoA. This reaction leads to an interesting biological phenomenon : when this reaction occurs in parallel of light emission reaction, we don't have a flash of light but a continuous light emission. This is because luciferin-AMP is a competitive inhibitor of the reaction whereas the luciferin-CoA is not. So the inhibition is deleted and the reaction continue to occur. | It has been found that the reaction between luciferin and CoA is possible, forming in a first step luciferin-AMP and then luciferin-CoA. This reaction leads to an interesting biological phenomenon : when this reaction occurs in parallel of light emission reaction, we don't have a flash of light but a continuous light emission. This is because luciferin-AMP is a competitive inhibitor of the reaction whereas the luciferin-CoA is not. So the inhibition is deleted and the reaction continue to occur. | ||
== Global Structure == | |||
== Function highlighted with structure == | |||
The most known reaction of luciferase is the light emission where luciferase uses luciferin, ATP and O2 as substrates. The color of emitted light varies according to the pH, which can be explained by the luciferase structure. But there are some other reactions which can uses fatty acids and coenzyme A. So the active site of the luciferase can theorically bind all these compounds. | |||
===Interactions with ligands=== | ===Interactions with ligands=== | ||
