Sandbox Reserved 951: Difference between revisions

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===Interactions with ligands===

The active site is not strictly highlighted according to the actual state of studies but some residues and motifs strongly modified have been determined and this conformation enables to find the active site. Many of these conserved residue are located on the core of the β-barrel and on the small C-terminal domain and in the surface of the N-terminal domain, which forms a depression. However, this depression is too large to enable interactions between residues and substrates, so it is thought that a conformational change occurs and sandwiches the substrates, forming the active site. This conformational change provide a suitable environment for light production because of water molecules will be excluded from the active site, favouring intramolecular reactions. Residues also follow a <scene name='60/604470/Cleft/1'>cleft</scene> caused by of the <scene name='60/604470/Beta_sheet_b/2'>β-sheet</scene> against the <scene name='60/604470/Beta_barrel/2'>β barrel</scene>.

The active site is not strictly highlighted according to the actual state of studies but some residues and motifs strongly modified have been determined and this conformation enables to find the active site. Many of these conserved residue are located on the core of the β-barrel and on the small C-terminal domain and in the surface of the N-terminal domain, which forms a <scene name='60/604470/Depression_c-ter_and_n-ter/1'>depression</scene>. However, this depression is too large to enable interactions between residues and substrates, so it is thought that a conformational change occurs and sandwiches the substrates, forming the active site. This conformational change provide a suitable environment for light production because of water molecules will be excluded from the active site, favouring intramolecular reactions. Residues also follow a <scene name='60/604470/Cleft/1'>cleft</scene> caused by of the <scene name='60/604470/Beta_sheet_b/2'>β-sheet</scene> against the <scene name='60/604470/Beta_barrel/2'>β barrel</scene>.

=====Interaction with ATP=====

Sandbox Reserved 951: Difference between revisions

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@@ Line 25: / Line 25: @@
 ===Interactions with ligands===
-The active site is not strictly highlighted according to the actual state of studies but some residues and motifs strongly modified have been determined and this conformation enables to find the active site. Many of these conserved residue are located on the core of the β-barrel and on the small C-terminal domain and in the surface of the N-terminal domain, which forms a depression. However, this depression is too large to enable interactions between residues and substrates, so it is thought that a conformational change occurs and sandwiches the substrates, forming the active site. This conformational change provide a suitable environment for light production because of water molecules will be excluded from the active site, favouring intramolecular reactions. Residues also follow a <scene name='60/604470/Cleft/1'>cleft</scene> caused by of the <scene name='60/604470/Beta_sheet_b/2'>β-sheet</scene> against the <scene name='60/604470/Beta_barrel/2'>β barrel</scene>.
+The active site is not strictly highlighted according to the actual state of studies but some residues and motifs strongly modified have been determined and this conformation enables to find the active site. Many of these conserved residue are located on the core of the β-barrel and on the small C-terminal domain and in the surface of the N-terminal domain, which forms a <scene name='60/604470/Depression_c-ter_and_n-ter/1'>depression</scene>. However, this depression is too large to enable interactions between residues and substrates, so it is thought that a conformational change occurs and sandwiches the substrates, forming the active site. This conformational change provide a suitable environment for light production because of water molecules will be excluded from the active site, favouring intramolecular reactions. Residues also follow a <scene name='60/604470/Cleft/1'>cleft</scene> caused by of the <scene name='60/604470/Beta_sheet_b/2'>β-sheet</scene> against the <scene name='60/604470/Beta_barrel/2'>β barrel</scene>.
 =====Interaction with ATP=====