Sandbox Reserved 962: Difference between revisions
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In eukaryotic cells the synthezise of mRNA is followed by a process of maturation. The best-known modifications are the polyadenylation, the splicing and the (Guanine-N7) capping. The capping is an important step of the maturation. It consists in adding a 7-methylguanosine on the first nucleotide of the mRNA with a diphosphate bonding. | In eukaryotic cells the synthezise of mRNA is followed by a process of maturation. The best-known modifications are the polyadenylation, the splicing and the (Guanine-N7) capping. The capping is an important step of the maturation. It consists in adding a 7-methylguanosine on the first nucleotide of the mRNA with a diphosphate bonding. | ||
One of the enzymes catalysing this reaction is the mRNA Cap (Guanine-N7) Methyltransferase. | |||
The cap allows the mRNA to be recognized by a protein complex which is involved in traduction initiation. | The cap allows the mRNA to be recognized by a protein complex which is involved in traduction initiation. | ||