Sandbox Reserved 970: Difference between revisions

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== Biological Function and Localisation ==
== Biological Function and Localisation ==


There are 3 types of calcium ATPase depending on their localization. The '''SERCA''' (Sarco/Endoplasmic Reticulum Calcium ATPase) is localized in the endoplasmic reticulum membranes, including the nuclear envelope. Only the structure of the SERCA has been resolved by x-ray crystallography. The '''PMCA''' (Plasma Membrane Calcium ATPase) is localized in plasma membranes. The '''SPCA''' (Secretory Pathway Calcium ATPase) is localized in the Golgi apparatus membranes. The particularity of this pump is that it is also able to transport Mn2+ ions.  
There are 3 types of calcium ATPases depending on their localization. The '''SERCA''' (Sarco/Endoplasmic Reticulum Calcium ATPase) is localized in the endoplasmic reticulum membranes, including the nuclear envelope. Only the structure of the SERCA has been resolved by x-ray crystallography. The '''PMCA''' (Plasma Membrane Calcium ATPase) is localized in plasma membranes. The '''SPCA''' (Secretory Pathway Calcium ATPase) is localized in the Golgi apparatus membranes. The particularity of this pump is that it is also able to transport Mn2+ ions.  


[[Image:ATPases.jpg|500px|center|]]
[[Image:ATPases.jpg|500px|center|]]