2j9y: Difference between revisions

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[[Image:2j9y.jpg|left|200px]]<br /><applet load="2j9y" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2j9y.jpg|left|200px]]
caption="2j9y, resolution 1.80&Aring;" />
 
'''TRYPTOPHAN SYNTHASE Q114N MUTANT IN COMPLEX WITH COMPOUND II'''<br />
{{Structure
|PDB= 2j9y |SIZE=350|CAPTION= <scene name='initialview01'>2j9y</scene>, resolution 1.80&Aring;
|SITE= <scene name='pdbsite=AC1:Foo+Binding+Site+For+Chain+B'>AC1</scene> and <scene name='pdbsite=AC2:Na+Binding+Site+For+Chain+B'>AC2</scene>
|LIGAND= <scene name='pdbligand=NA:SODIUM+ION'>NA</scene> and <scene name='pdbligand=FOO:'>FOO</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Tryptophan_synthase Tryptophan synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.20 4.2.1.20]
|GENE=
}}
 
'''TRYPTOPHAN SYNTHASE Q114N MUTANT IN COMPLEX WITH COMPOUND II'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2J9Y is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Salmonella_typhimurium Salmonella typhimurium] with <scene name='pdbligand=NA:'>NA</scene> and <scene name='pdbligand=FOO:'>FOO</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Tryptophan_synthase Tryptophan synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.20 4.2.1.20] Known structural/functional Sites: <scene name='pdbsite=AC1:Foo+Binding+Site+For+Chain+B'>AC1</scene> and <scene name='pdbsite=AC2:Na+Binding+Site+For+Chain+B'>AC2</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J9Y OCA].  
2J9Y is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Salmonella_typhimurium Salmonella typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2J9Y OCA].  


==Reference==
==Reference==
BetaQ114N and betaT110V mutations reveal a critically important role of the substrate alpha-carboxylate site in the reaction specificity of tryptophan synthase., Blumenstein L, Domratcheva T, Niks D, Ngo H, Seidel R, Dunn MF, Schlichting I, Biochemistry. 2007 Dec 11;46(49):14100-16. Epub 2007 Nov 16. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=18004874 18004874]
BetaQ114N and betaT110V mutations reveal a critically important role of the substrate alpha-carboxylate site in the reaction specificity of tryptophan synthase., Blumenstein L, Domratcheva T, Niks D, Ngo H, Seidel R, Dunn MF, Schlichting I, Biochemistry. 2007 Dec 11;46(49):14100-16. Epub 2007 Nov 16. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/18004874 18004874]
[[Category: Protein complex]]
[[Category: Protein complex]]
[[Category: Salmonella typhimurium]]
[[Category: Salmonella typhimurium]]
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[[Category: tryptophan biosynthesis]]
[[Category: tryptophan biosynthesis]]


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