4unp: Difference between revisions

Line 1:

'''~~Unreleased structure~~'''

==Mtb TMK in complex with compound 34==

~~The entry~~ 4unp is ~~ON HOLD~~

== Structural highlights ==

<table><tr><td colspan='2'>[[4unp]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UNP OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UNP FirstGlance].

~~Authors~~: ~~Read~~, J.A., ~~Hussein~~, S., ~~Gingell~~, H., ~~Tucker~~, J.

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=TXW:5-METHYL-7-PROPYL-1,6-NAPHTHYRIDIN-2(1H)-ONE'>TXW</scene></td></tr>

~~Description~~: ~~Mtb TMK in complex with compound 34~~

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/dTMP_kinase dTMP kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.9 2.7.4.9] </td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4unp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4unp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4unp RCSB], [http://www.ebi.ac.uk/pdbsum/4unp PDBsum]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/KTHY_MYCTO KTHY_MYCTO]] Catalyzes the reversible phosphorylation of deoxythymidine monophosphate (dTMP) to deoxythymidine diphosphate (dTDP), using ATP as its preferred phosphoryl donor. Situated at the junction of both de novo and salvage pathways of deoxythymidine triphosphate (dTTP) synthesis, is essential for DNA synthesis and cellular growth (By similarity).

__TOC__

</StructureSection>

[[Category: DTMP kinase]]

[[Category: Gingell, H]]

[[Category: Hussein, S]]

[[Category: Read, J A]]

[[Category: Tucker, J]]

[[Category: ~~Read, J.A~~]]

[[Category: Kinase]]

[[Category: ~~Gingell, H~~]]

[[Category: Transferase]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+==Mtb TMK in complex with compound 34==
+<StructureSection load='4unp' size='340' side='right' caption='[[4unp]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
-The entry 4unp is ON HOLD
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4unp]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4UNP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4UNP FirstGlance]. <br>
-Authors: Read, J.A., Hussein, S., Gingell, H., Tucker, J.
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=TXW:5-METHYL-7-PROPYL-1,6-NAPHTHYRIDIN-2(1H)-ONE'>TXW</scene></td></tr>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4unn|4unn]], [[4unq|4unq]], [[4unr|4unr]], [[4uns|4uns]]</td></tr>
-Description: Mtb TMK in complex with compound 34
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/dTMP_kinase dTMP kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.9 2.7.4.9] </span></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4unp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4unp OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4unp RCSB], [http://www.ebi.ac.uk/pdbsum/4unp PDBsum]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/KTHY_MYCTO KTHY_MYCTO]] Catalyzes the reversible phosphorylation of deoxythymidine monophosphate (dTMP) to deoxythymidine diphosphate (dTDP), using ATP as its preferred phosphoryl donor. Situated at the junction of both de novo and salvage pathways of deoxythymidine triphosphate (dTTP) synthesis, is essential for DNA synthesis and cellular growth (By similarity).
+__TOC__
+</StructureSection>
+[[Category: DTMP kinase]]
+[[Category: Gingell, H]]
 [[Category: Hussein, S]]
+[[Category: Read, J A]]
 [[Category: Tucker, J]]
-[[Category: Read, J.A]]
+[[Category: Kinase]]
-[[Category: Gingell, H]]
+[[Category: Transferase]]