4x01: Difference between revisions

Line 1:

'''~~Unreleased structure~~'''

==S. pombe Ctp1 tetramerization domain==

~~The entry~~ 4x01 is ~~ON HOLD until Paper Publication~~

== Structural highlights ==

<table><tr><td colspan='2'>[[4x01]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X01 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4X01 FirstGlance]. <br>

~~Authors~~: ~~Andres~~, S.N., ~~Williams~~, R.S.

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4x01 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x01 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4x01 RCSB], [http://www.ebi.ac.uk/pdbsum/4x01 PDBsum]</span></td></tr>

~~Description:~~

</table>

[[~~Category~~: ~~Unreleased Structures~~]]

== Function ==

[[Category: Andres, S.N]]

[[http://www.uniprot.org/uniprot/COM1_SCHPO COM1_SCHPO]] Endonuclease that cooperates with the MRN complex in processing meiotic and mitotic double-strand breaks by allowing the endonucleolytic removal of rec12 from the break sites and ensuring both resection and intrachromosomal association of the broken ends. Required for the formation of RPA-coated single strand DNA adjacent to the DSBs where it functions together with the MRN complex in 5'- 3' resection. Required for the repair of programmed meiotic DSBs. Involved also in an rhp51 recombinase-dependent recombinational repair pathway.<ref>PMID:16303567</ref> <ref>PMID:17936710</ref> <ref>PMID:18378696</ref> <ref>PMID:19139281</ref>

[[Category: Williams, R.S]]

== References ==

__TOC__

</StructureSection>

[[Category: Andres, S N]]

[[Category: Williams, R S]]

[[Category: Dna binding]]

[[Category: Dna double-strand break repair]]

[[Category: Four-helix bundle]]

[[Category: Homologous recombination]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
+==S. pombe Ctp1 tetramerization domain==
+<StructureSection load='4x01' size='340' side='right' caption='[[4x01]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
-The entry 4x01 is ON HOLD  until Paper Publication
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4x01]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4X01 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4X01 FirstGlance]. <br>
-Authors: Andres, S.N., Williams, R.S.
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4x01 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4x01 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4x01 RCSB], [http://www.ebi.ac.uk/pdbsum/4x01 PDBsum]</span></td></tr>
-Description:
+</table>
-[[Category: Unreleased Structures]]
+== Function ==
-[[Category: Andres, S.N]]
+[[http://www.uniprot.org/uniprot/COM1_SCHPO COM1_SCHPO]] Endonuclease that cooperates with the MRN complex in processing meiotic and mitotic double-strand breaks by allowing the endonucleolytic removal of rec12 from the break sites and ensuring both resection and intrachromosomal association of the broken ends. Required for the formation of RPA-coated single strand DNA adjacent to the DSBs where it functions together with the MRN complex in 5'- 3' resection. Required for the repair of programmed meiotic DSBs. Involved also in an rhp51 recombinase-dependent recombinational repair pathway.<ref>PMID:16303567</ref> <ref>PMID:17936710</ref> <ref>PMID:18378696</ref> <ref>PMID:19139281</ref>
-[[Category: Williams, R.S]]
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Andres, S N]]
+[[Category: Williams, R S]]
+[[Category: Dna binding]]
+[[Category: Dna double-strand break repair]]
+[[Category: Four-helix bundle]]
+[[Category: Homologous recombination]]