2jfa: Difference between revisions
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[[Image:2jfa.gif|left|200px]] | [[Image:2jfa.gif|left|200px]] | ||
'''ESTROGEN RECEPTOR ALPHA LBD IN COMPLEX WITH AN AFFINITY-SELECTED COREPRESSOR PEPTIDE''' | {{Structure | ||
|PDB= 2jfa |SIZE=350|CAPTION= <scene name='initialview01'>2jfa</scene>, resolution 2.55Å | |||
|SITE= <scene name='pdbsite=AC1:So4+Binding+Site+For+Chain+B'>AC1</scene> | |||
|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene> and <scene name='pdbligand=RAL:RALOXIFENE'>RAL</scene> | |||
|ACTIVITY= | |||
|GENE= | |||
}} | |||
'''ESTROGEN RECEPTOR ALPHA LBD IN COMPLEX WITH AN AFFINITY-SELECTED COREPRESSOR PEPTIDE''' | |||
==Disease== | ==Disease== | ||
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==About this Structure== | ==About this Structure== | ||
2JFA is a [ | 2JFA is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JFA OCA]. | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: zinc-finger]] | [[Category: zinc-finger]] | ||
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:41:07 2008'' | ||
Revision as of 15:41, 20 March 2008
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| 2jfa, resolution 2.55Å | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sites: | AC1 | ||||||||||||
| Ligands: | SO4 and RAL | ||||||||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||||||||
ESTROGEN RECEPTOR ALPHA LBD IN COMPLEX WITH AN AFFINITY-SELECTED COREPRESSOR PEPTIDE
Disease
Known diseases associated with this structure: Atherosclerosis, susceptibility to OMIM:[133430], Breast cancer OMIM:[133430], Estrogen resistance OMIM:[133430], HDL response to hormone replacement, augmented OMIM:[133430], Migraine, susceptibility to OMIM:[133430], Myocardial infarction, susceptibility to OMIM:[133430]
About this Structure
2JFA is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Thu Mar 20 17:41:07 2008
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Single protein
- Gustafsson, J A.
- Heldring, N.
- Mcdonnell, D.
- Pawson, T.
- Pike, A C.W.
- Treuter, E.
- RAL
- SO4
- Alternative splicing
- Corepressor
- Dna-binding
- Ligand-binding domain (lbd)
- Lipid-binding
- Metal-binding
- Nuclear protein
- Nuclear receptor
- Peptide antagonist
- Phage display
- Phosphorylation
- Polymorphism
- Receptor
- Steroid-binding
- Transcription
- Transcription factor
- Transcription regulation
- Zinc
- Zinc-finger
