2nq8: Difference between revisions

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[[Image:2nq8.jpg|left|200px]]<br /><applet load="2nq8" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2nq8.jpg|left|200px]]
caption="2nq8, resolution 2.50&Aring;" />
 
'''Malarial enoyl acyl ACP reductase bound with INH-NAD adduct'''<br />
{{Structure
|PDB= 2nq8 |SIZE=350|CAPTION= <scene name='initialview01'>2nq8</scene>, resolution 2.50&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=ZID:ISONICOTINIC-ACETYL-NICOTINAMIDE-ADENINE DINUCLEOTIDE'>ZID</scene>
|ACTIVITY=
|GENE= FabI ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5833 Plasmodium falciparum])
}}
 
'''Malarial enoyl acyl ACP reductase bound with INH-NAD adduct'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2NQ8 is a [http://en.wikipedia.org/wiki/Protein_complex Protein complex] structure of sequences from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum] with <scene name='pdbligand=ZID:'>ZID</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NQ8 OCA].  
2NQ8 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2NQ8 OCA].  


==Reference==
==Reference==
X-ray structural analysis of Plasmodium falciparum enoyl acyl carrier protein reductase as a pathway toward the optimization of triclosan antimalarial efficacy., Freundlich JS, Wang F, Tsai HC, Kuo M, Shieh HM, Anderson JW, Nkrumah LJ, Valderramos JC, Yu M, Kumar TR, Valderramos SG, Jacobs WR Jr, Schiehser GA, Jacobus DP, Fidock DA, Sacchettini JC, J Biol Chem. 2007 Aug 31;282(35):25436-44. Epub 2007 Jun 13. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17567585 17567585]
X-ray structural analysis of Plasmodium falciparum enoyl acyl carrier protein reductase as a pathway toward the optimization of triclosan antimalarial efficacy., Freundlich JS, Wang F, Tsai HC, Kuo M, Shieh HM, Anderson JW, Nkrumah LJ, Valderramos JC, Yu M, Kumar TR, Valderramos SG, Jacobs WR Jr, Schiehser GA, Jacobus DP, Fidock DA, Sacchettini JC, J Biol Chem. 2007 Aug 31;282(35):25436-44. Epub 2007 Jun 13. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17567585 17567585]
[[Category: Plasmodium falciparum]]
[[Category: Plasmodium falciparum]]
[[Category: Protein complex]]
[[Category: Protein complex]]
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[[Category: pfenr; inh; malaria]]
[[Category: pfenr; inh; malaria]]


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