2w06: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2w06]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W06 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W06 FirstGlance]. <br> | <table><tr><td colspan='2'>[[2w06]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W06 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W06 FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FRV:4-{[4-(1-CYCLOPROPYL-2-METHYL-1H-IMIDAZOL-5-YL)PYRIMIDIN-2-YL]AMINO}-N-METHYLBENZENESULFONAMIDE'>FRV</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FRV:4-{[4-(1-CYCLOPROPYL-2-METHYL-1H-IMIDAZOL-5-YL)PYRIMIDIN-2-YL]AMINO}-N-METHYLBENZENESULFONAMIDE'>FRV</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr> | <tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACE:ACETYL+GROUP'>ACE</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1pye|1pye]], [[1h08|1h08]], [[2vth|2vth]], [[2b53|2b53]], [[1v1k|1v1k]], [[1okv|1okv]], [[1ke7|1ke7]], [[1h25|1h25]], [[1pxk|1pxk]], [[2bhh|2bhh]], [[2vta|2vta]], [[2uue|2uue]], [[1gz8|1gz8]], [[1e1v|1e1v]], [[1ol2|1ol2]], [[1h27|1h27]], [[1jsv|1jsv]], [[2b52|2b52]], [[1ke5|1ke5]], [[1fin|1fin]], [[2c5o|2c5o]], [[2c68|2c68]], [[2vtt|2vtt]], [[1p2a|1p2a]], [[2vtq|2vtq]], [[2c4g|2c4g]], [[1w0x|1w0x]], [[1h1q|1h1q]], [[2w05|2w05]], [[1pxo|1pxo]], [[1ke9|1ke9]], [[2a0c|2a0c]], [[1hck|1hck]], [[1jsu|1jsu]], [[1pxn|1pxn]], [[2uze|2uze]], [[2vtm|2vtm]], [[2v0d|2v0d]], [[1oiq|1oiq]], [[1h1r|1h1r]], [[2iw8|2iw8]], [[1gih|1gih]], [[1hcl|1hcl]], [[1pw2|1pw2]], [[2vtn|2vtn]], [[1jst|1jst]], [[1oiu|1oiu]], [[1pxm|1pxm]], [[1b38|1b38]], [[1fq1|1fq1]], [[1vyw|1vyw]], [[1h1p|1h1p]], [[2c69|2c69]], [[1urc|1urc]], [[1pxi|1pxi]], [[2c6i|2c6i]], [[1ykr|1ykr]], [[2uzd|2uzd]], [[2c6k|2c6k]], [[2c5y|2c5y]], [[1wcc|1wcc]], [[2j9m|2j9m]], [[1vyz|1vyz]], [[2vti|2vti]], [[1jvp|1jvp]], [[1w98|1w98]], [[1pkd|1pkd]], [[1p5e|1p5e]], [[2vts|2vts]], [[2c5p|2c5p]], [[2uzn|2uzn]], [[2b54|2b54]], [[1ke6|1ke6]], [[1pxj|1pxj]], [[2uzl|2uzl]], [[2cci|2cci]], [[2bkz|2bkz]], [[2g9x|2g9x]], [[1y91|1y91]], [[2iw6|2iw6]], [[1gij|1gij]], [[1r78|1r78]], [[1h0v|1h0v]], [[2iw9|2iw9]], [[1w8c|1w8c]], [[1buh|1buh]], [[2bpm|2bpm]], [[2bts|2bts]], [[1fvv|1fvv]], [[1okw|1okw]], [[2vtp|2vtp]], [[2a4l|2a4l]], [[2c6t|2c6t]], [[1fvt|1fvt]], [[1qmz|1qmz]], [[2vu3|2vu3]], [[1ogu|1ogu]], [[2b55|2b55]], [[1pf8|1pf8]], [[1h1s|1h1s]], [[2c5v|2c5v]], [[2jgz|2jgz]], [[2bhe|2bhe]], [[1urw|1urw]], [[1oiy|1oiy]], [[2c6l|2c6l]], [[1f5q|1f5q]], [[2c6o|2c6o]], [[2vtl|2vtl]], [[1ol1|1ol1]], [[1h01|1h01]], [[2uzb|2uzb]], [[1oir|1oir]], [[1oi9|1oi9]], [[2vtj|2vtj]], [[2cjm|2cjm]], [[2c5n|2c5n]], [[2c5x|2c5x]], [[2c6m|2c6m]], [[1oit|1oit]], [[2v22|2v22]], [[1gy3|1gy3]], [[2vv9|2vv9]], [[1gii|1gii]], [[1di8|1di8]], [[1e9h|1e9h]], [[2vto|2vto]], [[1dm2|1dm2]], [[2uzo|2uzo]], [[1h24|1h24]], [[1h00|1h00]], [[2exm|2exm]], [[2clx|2clx]], [[1pxp|1pxp]], [[2cch|2cch]], [[1b39|1b39]], [[2btr|2btr]], [[1aq1|1aq1]], [[1h0w|1h0w]], [[1g5s|1g5s]], [[1ckp|1ckp]], [[1ke8|1ke8]], [[1h28|1h28]], [[1pxl|1pxl]], [[2vtr|2vtr]], [[1h26|1h26]], [[1e1x|1e1x]], [[1h07|1h07]], [[1y8y|1y8y]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1pye|1pye]], [[1h08|1h08]], [[2vth|2vth]], [[2b53|2b53]], [[1v1k|1v1k]], [[1okv|1okv]], [[1ke7|1ke7]], [[1h25|1h25]], [[1pxk|1pxk]], [[2bhh|2bhh]], [[2vta|2vta]], [[2uue|2uue]], [[1gz8|1gz8]], [[1e1v|1e1v]], [[1ol2|1ol2]], [[1h27|1h27]], [[1jsv|1jsv]], [[2b52|2b52]], [[1ke5|1ke5]], [[1fin|1fin]], [[2c5o|2c5o]], [[2c68|2c68]], [[2vtt|2vtt]], [[1p2a|1p2a]], [[2vtq|2vtq]], [[2c4g|2c4g]], [[1w0x|1w0x]], [[1h1q|1h1q]], [[2w05|2w05]], [[1pxo|1pxo]], [[1ke9|1ke9]], [[2a0c|2a0c]], [[1hck|1hck]], [[1jsu|1jsu]], [[1pxn|1pxn]], [[2uze|2uze]], [[2vtm|2vtm]], [[2v0d|2v0d]], [[1oiq|1oiq]], [[1h1r|1h1r]], [[2iw8|2iw8]], [[1gih|1gih]], [[1hcl|1hcl]], [[1pw2|1pw2]], [[2vtn|2vtn]], [[1jst|1jst]], [[1oiu|1oiu]], [[1pxm|1pxm]], [[1b38|1b38]], [[1fq1|1fq1]], [[1vyw|1vyw]], [[1h1p|1h1p]], [[2c69|2c69]], [[1urc|1urc]], [[1pxi|1pxi]], [[2c6i|2c6i]], [[1ykr|1ykr]], [[2uzd|2uzd]], [[2c6k|2c6k]], [[2c5y|2c5y]], [[1wcc|1wcc]], [[2j9m|2j9m]], [[1vyz|1vyz]], [[2vti|2vti]], [[1jvp|1jvp]], [[1w98|1w98]], [[1pkd|1pkd]], [[1p5e|1p5e]], [[2vts|2vts]], [[2c5p|2c5p]], [[2uzn|2uzn]], [[2b54|2b54]], [[1ke6|1ke6]], [[1pxj|1pxj]], [[2uzl|2uzl]], [[2cci|2cci]], [[2bkz|2bkz]], [[2g9x|2g9x]], [[1y91|1y91]], [[2iw6|2iw6]], [[1gij|1gij]], [[1r78|1r78]], [[1h0v|1h0v]], [[2iw9|2iw9]], [[1w8c|1w8c]], [[1buh|1buh]], [[2bpm|2bpm]], [[2bts|2bts]], [[1fvv|1fvv]], [[1okw|1okw]], [[2vtp|2vtp]], [[2a4l|2a4l]], [[2c6t|2c6t]], [[1fvt|1fvt]], [[1qmz|1qmz]], [[2vu3|2vu3]], [[1ogu|1ogu]], [[2b55|2b55]], [[1pf8|1pf8]], [[1h1s|1h1s]], [[2c5v|2c5v]], [[2jgz|2jgz]], [[2bhe|2bhe]], [[1urw|1urw]], [[1oiy|1oiy]], [[2c6l|2c6l]], [[1f5q|1f5q]], [[2c6o|2c6o]], [[2vtl|2vtl]], [[1ol1|1ol1]], [[1h01|1h01]], [[2uzb|2uzb]], [[1oir|1oir]], [[1oi9|1oi9]], [[2vtj|2vtj]], [[2cjm|2cjm]], [[2c5n|2c5n]], [[2c5x|2c5x]], [[2c6m|2c6m]], [[1oit|1oit]], [[2v22|2v22]], [[1gy3|1gy3]], [[2vv9|2vv9]], [[1gii|1gii]], [[1di8|1di8]], [[1e9h|1e9h]], [[2vto|2vto]], [[1dm2|1dm2]], [[2uzo|2uzo]], [[1h24|1h24]], [[1h00|1h00]], [[2exm|2exm]], [[2clx|2clx]], [[1pxp|1pxp]], [[2cch|2cch]], [[1b39|1b39]], [[2btr|2btr]], [[1aq1|1aq1]], [[1h0w|1h0w]], [[1g5s|1g5s]], [[1ckp|1ckp]], [[1ke8|1ke8]], [[1h28|1h28]], [[1pxl|1pxl]], [[2vtr|2vtr]], [[1h26|1h26]], [[1e1x|1e1x]], [[1h07|1h07]], [[1y8y|1y8y]]</td></tr> | ||
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cyclin-dependent_kinase Cyclin-dependent kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.22 2.7.11.22] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cyclin-dependent_kinase Cyclin-dependent kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.22 2.7.11.22] </span></td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w06 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w06 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2w06 RCSB], [http://www.ebi.ac.uk/pdbsum/2w06 PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w06 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w06 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2w06 RCSB], [http://www.ebi.ac.uk/pdbsum/2w06 PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
| Line 36: | Line 36: | ||
[[Category: Cyclin-dependent kinase]] | [[Category: Cyclin-dependent kinase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Anderson, M | [[Category: Anderson, M]] | ||
[[Category: Andrews, D M | [[Category: Andrews, D M]] | ||
[[Category: Barker, A J | [[Category: Barker, A J]] | ||
[[Category: Brassington, C A | [[Category: Brassington, C A]] | ||
[[Category: Byth, K F | [[Category: Byth, K F]] | ||
[[Category: Culshaw, J D | [[Category: Culshaw, J D]] | ||
[[Category: Finlay, M R.V | [[Category: Finlay, M R.V]] | ||
[[Category: Fisher, E | [[Category: Fisher, E]] | ||
[[Category: Green, C P | [[Category: Green, C P]] | ||
[[Category: Heaton, D W | [[Category: Heaton, D W]] | ||
[[Category: Mcmiken, H H.J | [[Category: Mcmiken, H H.J]] | ||
[[Category: Nash, I A | [[Category: Nash, I A]] | ||
[[Category: Newcombe, N J | [[Category: Newcombe, N J]] | ||
[[Category: Oakes, S E | [[Category: Oakes, S E]] | ||
[[Category: Roberts, A | [[Category: Roberts, A]] | ||
[[Category: Stanway, J J | [[Category: Stanway, J J]] | ||
[[Category: Thomas, A P | [[Category: Thomas, A P]] | ||
[[Category: Tucker, J A | [[Category: Tucker, J A]] | ||
[[Category: Weir, H M | [[Category: Weir, H M]] | ||
[[Category: Atp-binding]] | [[Category: Atp-binding]] | ||
[[Category: Cell cycle]] | [[Category: Cell cycle]] | ||
Revision as of 14:48, 19 January 2015
STRUCTURE OF CDK2 IN COMPLEX WITH AN IMIDAZOLYL PYRIMIDINE, COMPOUND 5C
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Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Cyclin-dependent kinase
- Homo sapiens
- Anderson, M
- Andrews, D M
- Barker, A J
- Brassington, C A
- Byth, K F
- Culshaw, J D
- Finlay, M R.V
- Fisher, E
- Green, C P
- Heaton, D W
- Mcmiken, H H.J
- Nash, I A
- Newcombe, N J
- Oakes, S E
- Roberts, A
- Stanway, J J
- Thomas, A P
- Tucker, J A
- Weir, H M
- Atp-binding
- Cell cycle
- Cell division
- Kinase
- Mitosis
- Nucleotide-binding
- Phosphoprotein
- Phosphorylation
- Serine/threonine-protein kinase
- Transferase
