2w9z: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2w9z]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W9Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W9Z FirstGlance]. <br> | <table><tr><td colspan='2'>[[2w9z]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W9Z OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W9Z FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2w99|2w99]], [[2w96|2w96]], [[2w9f|2w9f]], [[1ld2|1ld2]]</td></tr> | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2w99|2w99]], [[2w96|2w96]], [[2w9f|2w9f]], [[1ld2|1ld2]]</td></tr> | ||
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cyclin-dependent_kinase Cyclin-dependent kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.22 2.7.11.22] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cyclin-dependent_kinase Cyclin-dependent kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.22 2.7.11.22] </span></td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w9z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w9z OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2w9z RCSB], [http://www.ebi.ac.uk/pdbsum/2w9z PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w9z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w9z OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2w9z RCSB], [http://www.ebi.ac.uk/pdbsum/2w9z PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Disease == | == Disease == | ||
[[http://www.uniprot.org/uniprot/CDK4_HUMAN CDK4_HUMAN]] Defects in CDK4 are a cause of susceptibility to cutaneous malignant melanoma type 3 (CMM3) [MIM:[http://omim.org/entry/609048 609048]]. Malignant melanoma is a malignant neoplasm of melanocytes, arising de novo or from a pre-existing benign nevus, which occurs most often in the skin but also may involve other sites.<ref>PMID:7652577</ref> <ref>PMID:8528263</ref> <ref>PMID:9311594</ref> <ref>PMID:9425228</ref> | [[http://www.uniprot.org/uniprot/CDK4_HUMAN CDK4_HUMAN]] Defects in CDK4 are a cause of susceptibility to cutaneous malignant melanoma type 3 (CMM3) [MIM:[http://omim.org/entry/609048 609048]]. Malignant melanoma is a malignant neoplasm of melanocytes, arising de novo or from a pre-existing benign nevus, which occurs most often in the skin but also may involve other sites.<ref>PMID:7652577</ref> <ref>PMID:8528263</ref> <ref>PMID:9311594</ref> <ref>PMID:9425228</ref> | ||
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[[Category: Cyclin-dependent kinase]] | [[Category: Cyclin-dependent kinase]] | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Chopra, R | [[Category: Chopra, R]] | ||
[[Category: Cleasby, A | [[Category: Cleasby, A]] | ||
[[Category: Coyle, J E | [[Category: Coyle, J E]] | ||
[[Category: Day, P J | [[Category: Day, P J]] | ||
[[Category: Holding, F P | [[Category: Holding, F P]] | ||
[[Category: Jhoti, H | [[Category: Jhoti, H]] | ||
[[Category: Lengauer, C | [[Category: Lengauer, C]] | ||
[[Category: Mcmenamin, R L | [[Category: Mcmenamin, R L]] | ||
[[Category: Reilly, M O | [[Category: Reilly, M O]] | ||
[[Category: Tickle, I J | [[Category: Tickle, I J]] | ||
[[Category: Yon, J | [[Category: Yon, J]] | ||
[[Category: Cell cycle]] | [[Category: Cell cycle]] | ||
[[Category: Cyclin dependent kinase]] | [[Category: Cyclin dependent kinase]] | ||
