2o3v: Difference between revisions

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[[Image:2o3v.gif|left|200px]]~~<br /><applet load~~="2o3v~~" size~~="350~~" color~~=~~"white" frame~~=~~"true" align="right" spinBox="true"~~

[[Image:2o3v.gif|left|200px]]

~~caption="~~2o3v, resolution 2.800Å" />

'''Crystal Structure of the Homo sapiens Cytoplasmic Ribosomal Decoding Site complexed with paromamine derivative NB33'''~~<br />~~

{{Structure

|PDB= 2o3v |SIZE=350|CAPTION= <scene name='initialview01'>2o3v</scene>, resolution 2.800Å

|SITE=

|LIGAND= <scene name='pdbligand=N33:(2S,3R,4R,5S,6R)-3-AMINO-4-({[(2S,3R,4R,5S,6R)-3-AMINO-2-{[(1R,2R,3S,4R,6S)-4,6-DIAMINO-2,3-DIHYDROXYCYCLOHEXYL]OXY}-5-HYDROXY-6-(HYDROXYMETHYL)TETRAHYDRO-2H-PYRAN-4-YL]OXY}METHOXY)-6-(HYDROXYMETHYL)TETRAHYDRO-2H-PYRAN-2,5-DIOL'>N33</scene>

|ACTIVITY=

|GENE=

}}

'''Crystal Structure of the Homo sapiens Cytoplasmic Ribosomal Decoding Site complexed with paromamine derivative NB33'''

==Overview==

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==About this Structure==

2O3V is a [~~http://en.wikipedia.org/wiki/Single_protein~~ Single protein] structure of sequence from [http://en.wikipedia.org/wiki/ ~~] with <scene name='pdbligand=N33:'>N33</scene> as [http://en.wikipedia.org/wiki/ligand ligand~~]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O3V OCA].

2O3V is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O3V OCA].

==Reference==

Differential selectivity of natural and synthetic aminoglycosides towards the eukaryotic and prokaryotic decoding A sites., Kondo J, Hainrichson M, Nudelman I, Shallom-Shezifi D, Barbieri CM, Pilch DS, Westhof E, Baasov T, Chembiochem. 2007 Sep 24;8(14):1700-9. PMID:[http://~~ispc~~.~~weizmann~~.ac.~~il/~~/~~pmbin~~/~~getpm?pmid=~~17705310 17705310]

Differential selectivity of natural and synthetic aminoglycosides towards the eukaryotic and prokaryotic decoding A sites., Kondo J, Hainrichson M, Nudelman I, Shallom-Shezifi D, Barbieri CM, Pilch DS, Westhof E, Baasov T, Chembiochem. 2007 Sep 24;8(14):1700-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17705310 17705310]

[[Category: Single protein]]

[[Category: Baasov, T.]]

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[[Category: N33]]

[[Category: aminoglycoside]]

[[Category: ~~antibiotics~~]]

[[Category: antibiotic]]

[[Category: cytoplasmic]]

[[Category: decoding site]]

[[Category: eukaryote]]

[[Category: homo ~~sapiens~~]]

[[Category: homo sapien]]

[[Category: ribosome]]

[[Category: rna]]

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[[Category: translation inhibition]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu ~~Feb 21 18~~:14:09 2008''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:54:46 2008''

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@@ Line 1: / Line 1: @@
-[[Image:2o3v.gif|left|200px]]<br /><applet load="2o3v" size="350" color="white" frame="true" align="right" spinBox="true"
+[[Image:2o3v.gif|left|200px]]
-caption="2o3v, resolution 2.800&Aring;" />
-'''Crystal Structure of the Homo sapiens Cytoplasmic Ribosomal Decoding Site complexed with paromamine derivative NB33'''<br />
+ {{Structure
+|PDB= 2o3v |SIZE=350|CAPTION= <scene name='initialview01'>2o3v</scene>, resolution 2.800&Aring;
+|SITE=
+|LIGAND= <scene name='pdbligand=N33:(2S,3R,4R,5S,6R)-3-AMINO-4-({[(2S,3R,4R,5S,6R)-3-AMINO-2-{[(1R,2R,3S,4R,6S)-4,6-DIAMINO-2,3-DIHYDROXYCYCLOHEXYL]OXY}-5-HYDROXY-6-(HYDROXYMETHYL)TETRAHYDRO-2H-PYRAN-4-YL]OXY}METHOXY)-6-(HYDROXYMETHYL)TETRAHYDRO-2H-PYRAN-2,5-DIOL'>N33</scene>
+|ACTIVITY=
+|GENE=
+}}
+'''Crystal Structure of the Homo sapiens Cytoplasmic Ribosomal Decoding Site complexed with paromamine derivative NB33'''
 ==Overview==
@@ Line 7: / Line 16: @@
 ==About this Structure==
-O3V is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/ ] with <scene name='pdbligand=N33:'>N33</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O3V OCA].
+O3V is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O3V OCA].
 ==Reference==
-Differential selectivity of natural and synthetic aminoglycosides towards the eukaryotic and prokaryotic decoding A sites., Kondo J, Hainrichson M, Nudelman I, Shallom-Shezifi D, Barbieri CM, Pilch DS, Westhof E, Baasov T, Chembiochem. 2007 Sep 24;8(14):1700-9. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17705310 17705310]
+Differential selectivity of natural and synthetic aminoglycosides towards the eukaryotic and prokaryotic decoding A sites., Kondo J, Hainrichson M, Nudelman I, Shallom-Shezifi D, Barbieri CM, Pilch DS, Westhof E, Baasov T, Chembiochem. 2007 Sep 24;8(14):1700-9. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17705310 17705310]
 [[Category: Single protein]]
 [[Category: Baasov, T.]]
@@ Line 20: / Line 29: @@
 [[Category: N33]]
 [[Category: aminoglycoside]]
-[[Category: antibiotics]]
+[[Category: antibiotic]]
 [[Category: cytoplasmic]]
 [[Category: decoding site]]
 [[Category: eukaryote]]
-[[Category: homo sapiens]]
+[[Category: homo sapien]]
 [[Category: ribosome]]
 [[Category: rna]]
@@ Line 30: / Line 39: @@
 [[Category: translation inhibition]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 18:14:09 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 17:54:46 2008''