2o54: Difference between revisions

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[[Image:2o54.gif|left|200px]]<br /><applet load="2o54" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2o54.gif|left|200px]]
caption="2o54, resolution 2.500&Aring;" />
 
'''Structure of E. coli topoisomerase III in complex with an 8-base single stranded oligonucleotide. Frozen in glycerol at pH 7.0'''<br />
{{Structure
|PDB= 2o54 |SIZE=350|CAPTION= <scene name='initialview01'>2o54</scene>, resolution 2.500&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene> and <scene name='pdbligand=ACY:ACETIC ACID'>ACY</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/DNA_topoisomerase DNA topoisomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.99.1.2 5.99.1.2]
|GENE= topB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
}}
 
'''Structure of E. coli topoisomerase III in complex with an 8-base single stranded oligonucleotide. Frozen in glycerol at pH 7.0'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2O54 is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] with <scene name='pdbligand=CL:'>CL</scene> and <scene name='pdbligand=ACY:'>ACY</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/DNA_topoisomerase DNA topoisomerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.99.1.2 5.99.1.2] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O54 OCA].  
2O54 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2O54 OCA].  


==Reference==
==Reference==
Structural studies of E. coli topoisomerase III-DNA complexes reveal a novel type IA topoisomerase-DNA conformational intermediate., Changela A, DiGate RJ, Mondragon A, J Mol Biol. 2007 Apr 20;368(1):105-18. Epub 2007 Feb 3. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=17331537 17331537]
Structural studies of E. coli topoisomerase III-DNA complexes reveal a novel type IA topoisomerase-DNA conformational intermediate., Changela A, DiGate RJ, Mondragon A, J Mol Biol. 2007 Apr 20;368(1):105-18. Epub 2007 Feb 3. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17331537 17331537]
[[Category: DNA topoisomerase]]
[[Category: DNA topoisomerase]]
[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: topoisomerase type ia complex with sdna]]
[[Category: topoisomerase type ia complex with sdna]]


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