2oat: Difference between revisions

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[[Image:2oat.jpg|left|200px]]<br /><applet load="2oat" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2oat.jpg|left|200px]]
caption="2oat, resolution 1.95&Aring;" />
 
'''ORNITHINE AMINOTRANSFERASE COMPLEXED WITH 5-FLUOROMETHYLORNITHINE'''<br />
{{Structure
|PDB= 2oat |SIZE=350|CAPTION= <scene name='initialview01'>2oat</scene>, resolution 1.95&Aring;
|SITE= <scene name='pdbsite=FMA:The+Inhibitor-Cofactor+Adduct+Has+An+Absorption+Maximum+...'>FMA</scene>, <scene name='pdbsite=FMB:The+Inhibitor-Cofactor+Adduct+Has+An+Absorption+Maximum+...'>FMB</scene> and <scene name='pdbsite=FMC:The+Inhibitor-Cofactor+Adduct+Has+An+Absorption+Maximum+...'>FMC</scene>
|LIGAND= <scene name='pdbligand=PFM:1-AMINO-7-(2-METHYL-3-OXIDO-5-((PHOSPHONOXY)METHYL)-4-PYRIDOXAL-5-OXO-6-HEPTENATE'>PFM</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Ornithine_aminotransferase Ornithine aminotransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.13 2.6.1.13]
|GENE= OAT ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
}}
 
'''ORNITHINE AMINOTRANSFERASE COMPLEXED WITH 5-FLUOROMETHYLORNITHINE'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2OAT is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] with <scene name='pdbligand=PFM:'>PFM</scene> as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/Ornithine_aminotransferase Ornithine aminotransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.13 2.6.1.13] Known structural/functional Sites: <scene name='pdbsite=FMA:The+Inhibitor-Cofactor+Adduct+Has+An+Absorption+Maximum+...'>FMA</scene>, <scene name='pdbsite=FMB:The+Inhibitor-Cofactor+Adduct+Has+An+Absorption+Maximum+...'>FMB</scene> and <scene name='pdbsite=FMC:The+Inhibitor-Cofactor+Adduct+Has+An+Absorption+Maximum+...'>FMC</scene>. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OAT OCA].  
2OAT is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2OAT OCA].  


==Reference==
==Reference==
Crystal structure of human ornithine aminotransferase complexed with the highly specific and potent inhibitor 5-fluoromethylornithine., Storici P, Capitani G, Muller R, Schirmer T, Jansonius JN, J Mol Biol. 1999 Jan 8;285(1):297-309. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9878407 9878407]
Crystal structure of human ornithine aminotransferase complexed with the highly specific and potent inhibitor 5-fluoromethylornithine., Storici P, Capitani G, Muller R, Schirmer T, Jansonius JN, J Mol Biol. 1999 Jan 8;285(1):297-309. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9878407 9878407]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Ornithine aminotransferase]]
[[Category: Ornithine aminotransferase]]
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[[Category: pyridoxal phosphate]]
[[Category: pyridoxal phosphate]]


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