2wtj: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2wtj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WTJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WTJ FirstGlance]. <br> | <table><tr><td colspan='2'>[[2wtj]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WTJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WTJ FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=WTJ:2-AMINO-5-(2,3-DIHYDROTHIENO[3,4-B][1,4]DIOXIN-5-YL)-N-[2-(DIMETHYLAMINO)ETHYL]PYRIDINE-3-CARBOXAMIDE'>WTJ</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=WTJ:2-AMINO-5-(2,3-DIHYDROTHIENO[3,4-B][1,4]DIOXIN-5-YL)-N-[2-(DIMETHYLAMINO)ETHYL]PYRIDINE-3-CARBOXAMIDE'>WTJ</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2wti|2wti]], [[2wtc|2wtc]], [[2wtd|2wtd]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2wti|2wti]], [[2wtc|2wtc]], [[2wtd|2wtd]]</td></tr> | ||
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wtj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wtj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wtj RCSB], [http://www.ebi.ac.uk/pdbsum/2wtj PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wtj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wtj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wtj RCSB], [http://www.ebi.ac.uk/pdbsum/2wtj PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Non-specific serine/threonine protein kinase]] | [[Category: Non-specific serine/threonine protein kinase]] | ||
[[Category: Aherne, G W | [[Category: Aherne, G W]] | ||
[[Category: Allen, C E | [[Category: Allen, C E]] | ||
[[Category: Anderson, V E | [[Category: Anderson, V E]] | ||
[[Category: Antoni, L | [[Category: Antoni, L]] | ||
[[Category: Boxall, K | [[Category: Boxall, K]] | ||
[[Category: Burns, S | [[Category: Burns, S]] | ||
[[Category: Caldwell, J J | [[Category: Caldwell, J J]] | ||
[[Category: Collins, I | [[Category: Collins, I]] | ||
[[Category: Garrett, M D | [[Category: Garrett, M D]] | ||
[[Category: Hilton, S | [[Category: Hilton, S]] | ||
[[Category: Naud, S | [[Category: Naud, S]] | ||
[[Category: Oliver, A W | [[Category: Oliver, A W]] | ||
[[Category: Pearl, L H | [[Category: Pearl, L H]] | ||
[[Category: Cell cycle]] | [[Category: Cell cycle]] | ||
[[Category: Kinase]] | [[Category: Kinase]] | ||
[[Category: Li-fraumeni syndrome]] | [[Category: Li-fraumeni syndrome]] | ||
[[Category: Transferase]] | [[Category: Transferase]] | ||
Revision as of 08:00, 20 January 2015
CRYSTAL STRUCTURE OF CHK2 IN COMPLEX WITH AN INHIBITOR
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