2z5x: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2z5x]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z5X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Z5X FirstGlance]. <br> | <table><tr><td colspan='2'>[[2z5x]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z5X OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Z5X FirstGlance]. <br> | ||
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DCX:DECYL(DIMETHYL)PHOSPHINE+OXIDE'>DCX</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HRM:7-METHOXY-1-METHYL-9H-BETA-CARBOLINE'>HRM</scene>< | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DCX:DECYL(DIMETHYL)PHOSPHINE+OXIDE'>DCX</scene>, <scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HRM:7-METHOXY-1-METHYL-9H-BETA-CARBOLINE'>HRM</scene></td></tr> | ||
<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2z5y|2z5y]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2z5y|2z5y]]</td></tr> | ||
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Monoamine_oxidase Monoamine oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.3.4 1.4.3.4] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Monoamine_oxidase Monoamine oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.4.3.4 1.4.3.4] </span></td></tr> | ||
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2z5x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z5x OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2z5x RCSB], [http://www.ebi.ac.uk/pdbsum/2z5x PDBsum]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2z5x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z5x OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2z5x RCSB], [http://www.ebi.ac.uk/pdbsum/2z5x PDBsum]</span></td></tr> | ||
<table> | </table> | ||
== Disease == | == Disease == | ||
[[http://www.uniprot.org/uniprot/AOFA_HUMAN AOFA_HUMAN]] Defects in MAOA are the cause of Brunner syndrome (BRUNS) [MIM:[http://omim.org/entry/300615 300615]]. Brunner syndrome is a form of X-linked non-dysmorphic mild mental retardation. Male patients are affected by a syndrome of borderline mental retardation and exhibit abnormal behavior, including disturbed regulation of impulsive aggression. Obligate female carriers have normal intelligence and behavior. | [[http://www.uniprot.org/uniprot/AOFA_HUMAN AOFA_HUMAN]] Defects in MAOA are the cause of Brunner syndrome (BRUNS) [MIM:[http://omim.org/entry/300615 300615]]. Brunner syndrome is a form of X-linked non-dysmorphic mild mental retardation. Male patients are affected by a syndrome of borderline mental retardation and exhibit abnormal behavior, including disturbed regulation of impulsive aggression. Obligate female carriers have normal intelligence and behavior. | ||
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[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Monoamine oxidase]] | [[Category: Monoamine oxidase]] | ||
[[Category: Ma, J | [[Category: Ma, J]] | ||
[[Category: Son, S Y | [[Category: Son, S Y]] | ||
[[Category: Tsukihara, T | [[Category: Tsukihara, T]] | ||
[[Category: Yoshimura, M | [[Category: Yoshimura, M]] | ||
[[Category: Catecholamine metabolism]] | [[Category: Catecholamine metabolism]] | ||
[[Category: Dimethyldecylphosphine oxide]] | [[Category: Dimethyldecylphosphine oxide]] | ||
