2one: Difference between revisions

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[[Image:2one.gif|left|200px]]<br /><applet load="2one" size="350" color="white" frame="true" align="right" spinBox="true"
[[Image:2one.gif|left|200px]]
caption="2one, resolution 2.0&Aring;" />
 
'''ASYMMETRIC YEAST ENOLASE DIMER COMPLEXED WITH RESOLVED 2'-PHOSPHOGLYCERATE AND PHOSPHOENOLPYRUVATE'''<br />
{{Structure
|PDB= 2one |SIZE=350|CAPTION= <scene name='initialview01'>2one</scene>, resolution 2.0&Aring;
|SITE=
|LIGAND= <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=LI:LITHIUM+ION'>LI</scene>, <scene name='pdbligand=2PG:2-PHOSPHOGLYCERIC+ACID'>2PG</scene> and <scene name='pdbligand=PEP:PHOSPHOENOLPYRUVATE'>PEP</scene>
|ACTIVITY= [http://en.wikipedia.org/wiki/Phosphopyruvate_hydratase Phosphopyruvate hydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.11 4.2.1.11]
|GENE=
}}
 
'''ASYMMETRIC YEAST ENOLASE DIMER COMPLEXED WITH RESOLVED 2'-PHOSPHOGLYCERATE AND PHOSPHOENOLPYRUVATE'''
 


==Overview==
==Overview==
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==About this Structure==
==About this Structure==
2ONE is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae] with <scene name='pdbligand=MG:'>MG</scene>, <scene name='pdbligand=LI:'>LI</scene>, <scene name='pdbligand=2PG:'>2PG</scene> and <scene name='pdbligand=PEP:'>PEP</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. The following page contains interesting information on the relation of 2ONE with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb50_1.html The Glycolytic Enzymes]]. Active as [http://en.wikipedia.org/wiki/Phosphopyruvate_hydratase Phosphopyruvate hydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.11 4.2.1.11] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ONE OCA].  
2ONE is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. The following page contains interesting information on the relation of 2ONE with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb50_1.html The Glycolytic Enzymes]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ONE OCA].  


==Reference==
==Reference==
Mechanism of enolase: the crystal structure of asymmetric dimer enolase-2-phospho-D-glycerate/enolase-phosphoenolpyruvate at 2.0 A resolution., Zhang E, Brewer JM, Minor W, Carreira LA, Lebioda L, Biochemistry. 1997 Oct 14;36(41):12526-34. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=9376357 9376357]
Mechanism of enolase: the crystal structure of asymmetric dimer enolase-2-phospho-D-glycerate/enolase-phosphoenolpyruvate at 2.0 A resolution., Zhang E, Brewer JM, Minor W, Carreira LA, Lebioda L, Biochemistry. 1997 Oct 14;36(41):12526-34. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9376357 9376357]
[[Category: Phosphopyruvate hydratase]]
[[Category: Phosphopyruvate hydratase]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: lyase]]
[[Category: lyase]]


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